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Journal ArticleDOI

Alkaloids and coumarins from ruta chalepensis

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TLDR
The aerial parts of Ruta chalepensis yielded the alkaloids kokusaginine, skimmianine, arborinine, γ-fagarine, graveoline and the new alkaloid 3′-hydroxygraveoline as mentioned in this paper.
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This article is published in Phytochemistry.The article was published on 1986-01-01. It has received 41 citations till now. The article focuses on the topics: Ruta chalepensis & Isopimpinellin.

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Antifungal activity of plant extracts against dermatophytes.

TL;DR: The aqueous extracts of 22 plants used in folkloric medicine in Palestine were investigated for their antifungal activity and minimum inhibitory concentrations (MICs) against nine isolates of Microsporum canis, Trichophyton mentagrophytes and Trichopterton violaceum.
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Neuropharmacological profile of an ethanol extract of Ruta chalepensis L. in mice.

TL;DR: The sedative-hypnotic potentiation, anxiolytic, anticonvulsant and antinociceptive effects suggest that Ruta chalepensis induces a depressant activity on the CNS.
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High-resolution gas-chromatographic analysis of the secondary metabolites obtained by subcritical-fluid extraction from Colombian rue (Ruta graveolens L.)

TL;DR: The extraction method used has low environmental impact and produced solvent-free extracts in good yield with no pigments, waxes, resins, or high-molecular weight compounds which may interfere with the isolation and analysis of the alkaloids responsible for rue's biological activity, which were extracted in relatively high yield.
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Protection against murine endotoxemia by treatment with Ruta chalepensis L., a plant with anti-inflammatory properties.

TL;DR: Data show that Ruta Chalepensis L. (Rutaceae) possesses powerful immunopharmacological properties that make it capable of counteracting the lethal effects of high doses of LPS in vivo.
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Toxicity studies in mice of ethanol extracts of Foeniculum vulgare fruit and Ruta chalepensis aerial parts.

TL;DR: Both the extracts failed to show spermatotoxic effects and the treated male mice gained significant weight during chronic treatment while a loss or no significant change in weight was noticed in the female mice treated with the same extracts.
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