Open Access
Antibiotic sensitivity testing. Report of an international collaborative study.
H. M. Ericsson,J. C. Sherris +1 more
- Vol. 217
TLDR
A working party of people well known internationally in the field of antibiotic sensitivity testing was set up under World Health Organization sponsorship in 1961 to investigate the possibility of introducing standard techniques which might become universal reference methods.Abstract:
A working party of people well known internationally in the field of was set up under World Health Organization sponsorship in 1961 to study the reproducibility of antibiotic sensitivity testing. Their aim was to investigate the possibility of introducing standard techniques which might become universal reference methods. The work involved 16 laboratories. Each was provided with the same 16 organisms, supplies of standard media and antibiotics and precise instructions for their use. The Other CABI sites read more
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Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances
TL;DR: The aim of broth and agar dilution methods is to determine the lowest concentration of the assayed antimicrobial agent (minimal inhibitory concentration, MIC) that, under defined test conditions, inhibits the visible growth of the bacterium being investigated.
Book
Performance standards for antimicrobial susceptibility testing
Melvin P. Weinstein,Clinical +1 more
TL;DR: The tabular information presented here represents the most current information for drug selection, interpretation, and QC using the procedures standardized in the most recent editions of M02, M07, and M11, and users should replace outdated editions with the current editions of CLSI documents.
Book
Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically : Approved standard
Matthew A. Wikler,Clinical +1 more
TL;DR: This document describes standard broth dilution and microdilution and agar dilution techniques and it includes a series of procedures to standardize the way the tests are performed, and the performance, applications, and limitations of the current CLSI-recommended methods are described.
Journal ArticleDOI
Extended Broad-Spectrum β-Lactamases Conferring Transferable Resistance to Newer β-Lactam Agents in Enterobacteriaceae: Hospital Prevalence and Susceptibility Patterns
TL;DR: Before 1985 at the Pitié-Salpêtrière Hospital in Paris, resistance to cefotaxime in clinical isolates of Enterobacteriaceae involved only species producing inducible class 1 beta-lactamase; between November 1985 and April 1987, however, 62 isolates showed decreased susceptibility to cffotaximes, and these enzymes were designated EBS-Bla.
Journal ArticleDOI
Antimicrobial Susceptibility Testing: A Review of General Principles and Contemporary Practices
TL;DR: An important task of the clinical microbiology laboratory is the performance of antimicrobial susceptibility testing of significant bacterial isolates to detect possible drug resistance in common pathogens and to assure susceptibility to drugs of choice for particular infections.