Atypical lipoma, atypical intramuscular lipoma, and well differentiated retroperitoneal liposarcoma: a reappraisal of 30 cases formerly classified as well differentiated liposarcoma.
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TLDR
It is suggested that the term “well differentiated retroperitoneal liposarcoma” be retained for cases of this type, and atypical intramuscular lipoma is proposed for this group.Abstract:
Thirty cases formerly diagnosed as Grade I lipogenic liposarcoma (well differentiated liposarcoma) were reviewed. The basic histologic pattern in all was that of adult fat modified by the presence of cells with enlarged, hyperchromatic nuclei; in most cases there was also a component of myxoid and/or fibrous tissue. The length of follow-up ranged from two to 30 years. Nine of the tumors were located in the subcutaneous layer. None of these recurred after excision, not even those which were simply "shelled out," and none metastasized. The term "atypical lipoma" is proposed for this group. Thirteen were located within or between muscles of the limbs, limb girdles, and head and neck. Nine of these recurred at least one, but there were no metastases and no deaths due to tumor. These were designated "atypical intramuscular lipoma." The remaining eight originated in the retroperitoneum. Although none of these patients developed metastases, five suffered inoperable recurrence and three died as a result of the neoplasm. It is suggested that the term "well differentiated retroperitoneal liposarcoma" be retained for cases of this type.read more
Citations
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Mark D. Murphey,Mark D. Murphey,Mark D. Murphey,John F. Carroll,Donald J. Flemming,Donald J. Flemming,Thomas L. Pope,Thomas L. Pope,Francis H. Gannon,Mark J. Kransdorf +9 more
TL;DR: Understanding the spectrum of appearances of the various benign musculoskeletal lipomatous lesions improves radiologic assessment and is vital for optimal patient management.
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Dedifferentiated Liposarcoma: A Clinicopathological Analysis of 155 Cases with a Proposal for an Expanded Definition of Dedifferentiation
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References
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Spindle cell lipoma.
Franz M. Enzinger,Dean A. Harvey +1 more
TL;DR: Followup information obtained in 63 patients with this lesion revealed a uniformly favorable clinical course, indicating that local excision is the treatment of choice, and that there is no need or reason for radical surgical procedures.
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Liposarcoma. A clinical and pathological study of 53 cases
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Intermuscular and intramuscular lipomas and hibernomas. A clinical, roentgenologic, histologic, and prognostic study of 46 cases
TL;DR: Angiography in 2 patients with hibernoma showed that the tumor was highly vascular with irregular vessels and early venous filling, findings usually held as contributory signs of malignancy in the diagnosis of soft tissue tumors.
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Infiltrating lipomas and angiolipomas revisited.
TL;DR: Twenty‐seven soft tissue tumors composed of benign adipose tissue are presented featuring extensive local invasion and recurrence, although locally recurrent, neither has yet undergone malignant transformation.
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