Journal ArticleDOI
Autonomic Epilepsy: Clonidine Blockade of Paroxysmal Catecholamine Release and Flushing
TLDR
This patient represents a rare case of autonomic epilepsy with the seizure focus in the temporal lobe and an epileptic pathogenesis was suggested by stereotypic olfactory and epigastric prodromata before spells, and abolition of paroxysms with the anticonvulsant carbamazepine.Abstract:
We studied a 59-year-old man with transient paroxysms of hypertension, tachycardia, and flushing in whom pheochromocytoma was excluded. Although catecholamine excretion was normal, plasma ...read more
Citations
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A critical review of the pathophysiology of dysautonomia following traumatic brain injury
Ian J. Baguley,Roxana E. Heriseanu,Ian D. Cameron,Melissa Nott,Shameran Slewa-Younan,Shameran Slewa-Younan +5 more
TL;DR: A critical review of the competing theories against the available observational, clinical and neurotransmitter evidence suggests the EIR Model provides an explanatory model that encompasses other acute autonomic emergency syndromes, accommodates ‘triggering’ of paroxysms and provides a rationale for all known medication effects.
Journal ArticleDOI
Interictal autonomic nervous system function in patients with epilepsy.
TL;DR: The results showed that patients with epilepsy have greater BP and HR variability and reactivity than controls, attributable in part to CBZ levels.
Journal ArticleDOI
The flushing patient: Differential diagnosis, workup, and treatment
TL;DR: In this learning activity, participants should be familiar with the mechanisms of flushing, its clinical differential diagnosis, the approach to establish a definitive diagnosis, and management of various conditions that produce flushing.
Journal ArticleDOI
Cardiac manifestations of complex partial seizures
TL;DR: Six patients with complex partial seizures in whom the first or most prominent manifestation was cardiovascular are described, and a cluster of symptoms suggestive of pheochromocytoma developed in one.
Journal ArticleDOI
Management of autonomic dysfunction in severe tetanus: the use of magnesium sulphate and clonidine
TL;DR: The treatment of severe tetanus with autonomic dysfunction is discussed, with emphasis on the use of magnesium sulphate, and the previously unreported and successful use of clonidine to control sympathetic overactivity.
References
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Journal ArticleDOI
A relation between non-esterified fatty acids in plasma and the metabolism of glucose
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Immunoassay of Insulin: Two Antibody System: Plasma Insulin Levels of Normal, Subdiabetic and Diabetic Rats
Carl R Morgan,Arnold Lazarow +1 more
TL;DR: A two antibody system of insulin assay for immunoassay of insulin induces the production of specific nonprecipitating antibodies, both in experimental animals and in humans.
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Some Studies of the Protein-Binding of Steroids and Their Application to the Routine Micro and Ultramicro Measurement of Various Steroids in Body Fluids by Competitive Protein-Binding Radioassay
TL;DR: A 100-fold increase in sensitivity has now been achieved by using tritiated steroids in place of 14C-labeled steroids, by utilizing the CBG's of species other than man, and by using adsorption in Place of dialysis or gel filtration.
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Human prolactin and growth hormone release during surgery and other conditions of stress.
TL;DR: It is concluded that prolactin in human beings is at least as responsive as growth hormone to release by stress in most situations; the two hormones ...
Journal ArticleDOI
Diencephalic autonomic epilepsy
TL;DR: It is suggested that there are higher structures analogous to the cerebral motor cortex which are capable of producing, when irritated, paroxysmal motor discharges through the vegetative nervous system, similar to the focal discharging through the cerebrospinal system first described by Hughlings Jackson as epileptic.