M
McClellan M. Walther
Researcher at National Institutes of Health
Publications - 146
Citations - 19054
McClellan M. Walther is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Renal cell carcinoma & Kidney. The author has an hindex of 69, co-authored 146 publications receiving 18107 citations. Previous affiliations of McClellan M. Walther include National Institute of Standards and Technology.
Papers
More filters
Journal ArticleDOI
Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas
Laura S. Schmidt,Fuh Mei Duh,F. Chen,Takeshi Kishida,Gladys Glenn,Peter L. Choyke,Stephen W. Scherer,Zhengping Zhuang,Irina A. Lubensky,Michael Dean,Rando Allikmets,Abirami Chidambaram,Ulf S.R. Bergerheim,J. T. Feltis,C. Casadevall,A. Zamarron,M. Bernues,Stéphane Richard,C. J. M. Lips,McClellan M. Walther,Lap-Chee Tsui,Laura Geil,Mary Lou Orcutt,Thomas Stackhouse,J. Lipan,L. Slife,Hiltrud Brauch,Jochen Decker,G. Niehans,M. D. Hughson,Holger Moch,Stefan Storkel,Michael I. Lerman,W.M. Linehan,B. Zbar +34 more
TL;DR: The results suggest that missense mutations located in the MET proto-oncogene lead to constitutive activation of the MET protein and papillary renal carcinomas.
Journal ArticleDOI
von Hippel-Lindau disease
Russell R. Lonser,Gladys Glenn,McClellan M. Walther,Emily Y. Chew,Steven K. Libutti,W. Marston Linehan,Edward H. Oldfield +6 more
TL;DR: An overview of the clinical aspects, management, and treatment options for von Hippel-Lindau disease is presented.
Journal ArticleDOI
Biochemical diagnosis of pheochromocytoma: which test is best?
Jacques W.M. Lenders,Karel Pacak,McClellan M. Walther,W. Marston Linehan,Massimo Mannelli,Peter Friberg,Harry R. Keiser,David S. Goldstein,Graeme Eisenhofer +8 more
TL;DR: Plasma free metanephrines provide the best test for excluding or confirming pheochromocytoma and should be the test of first choice for diagnosis of the tumor.
Journal ArticleDOI
Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome.
Michael L. Nickerson,Michelle B. Warren,Jorge R. Toro,Vera Y. Matrosova,Gladys Glenn,Maria L. Turner,Paul H. Duray,Maria J. Merino,Peter L. Choyke,Christian P. Pavlovich,Nirmala Sharma,McClellan M. Walther,David J. Munroe,Robert Hill,Eamonn R. Maher,Cheryl R. Greenberg,Michael I. Lerman,W. Marston Linehan,Berton Zbar,Laura S. Schmidt +19 more
TL;DR: Discovery of disease-causing mutations in BHD, a novel kidney cancer gene associated with renal oncocytoma or chromophobe renal cancer, will contribute to understanding the role of folliculin in pathways common to skin, lung, and kidney development.
Journal ArticleDOI
Mutations in the fumarate hydratase gene cause hereditary leiomyomatosis and renal cell cancer in families in North America.
Jorge R. Toro,Michael L. Nickerson,Ming Hui Wei,Michelle B. Warren,Gladys Glenn,Maria L. Turner,Laveta Stewart,Paul H. Duray,Ousman Tourre,Nirmala Sharma,Peter L. Choyke,Pamela Stratton,Maria J. Merino,McClellan M. Walther,W. Marston Linehan,Laura S. Schmidt,Berton Zbar +16 more
TL;DR: The present study shows that mutations in FH are associated with HLRCC in North America, and expands the histologic spectrum of renal tumors and FH mutations associated withHLRCC.