Journal ArticleDOI
Azodisal sodium in the treatment of ulcerative colitis: A Study of tolerance and relapse-prevention properties
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TLDR
Azodisal sodium appears to be an effective agent for the maintenance treatment of ulcerative colitis and male fertility appeared to be unaffected.About:
This article is published in Gastroenterology.The article was published on 1986-04-01. It has received 180 citations till now. The article focuses on the topics: Sulfasalazine & Ulcerative colitis.read more
Citations
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Journal ArticleDOI
Ulcerative colitis practice guidelines in adults: American College Of Gastroenterology, Practice Parameters Committee.
Asher Kornbluth,David B. Sachar +1 more
TL;DR: Guidelines for clinical practice are aimed to indicate preferred approaches to medical problems as established by scientifically valid research, and are applicable to all physicians who address the subject regardless of specialty training or interests.
Journal ArticleDOI
Inflammatory bowel disease: clinical aspects and established and evolving therapies.
TL;DR: The current diagnostic approach, their pathology, natural course, and common complications, the assessment of disease activity, extraintestinal manifestations, and medical and surgical management are discussed, and diagnostic and therapeutic algorithms are provided.
Journal ArticleDOI
Second European evidence-based consensus on the diagnosis and management of ulcerative colitis Part 2: Current management
Axel Dignass,James O. Lindsay,Andreas Sturm,Alastair Windsor,Jean-Frederic Colombel,Mathieu Allez,G. D'Haens,André D'Hoore,Gerassimos J. Mantzaris,Gottfried Novacek,Tom Øresland,Walter Reinisch,Miquel Sans,Eduard F. Stange,Severine Vermeire,Simon Travis,Gert Van Assche +16 more
TL;DR: The most widely used index for severe UC remains that of Truelove and Witts3: any patient who has a bloody stool frequency ≥ 6/day and a tachycardia (> 90 bpm), or temperature > 37.8 °C, or anaemia (haemoglobin 30 mm/h) has severe ulcerative colitis (Table 1.3) as mentioned in this paper.
Second European evidence-based Consensus on the diagnosis and management of ulcerative colitis: Current management
Axel Dignass,James O. Lindsay,Andreas Sturm,Alastair Windsor,Jean-Frédéric Colombel,Mathieu Allez,G. D'Haens,André D'Hoore,Gerassimos J. Mantzaris,Gottfried Novacek,Tom Øresland,W. Reinisch,Miquel Sans,Eduard F. Stange,Severine Vermeire,Simon Travis,Gert A. Van Assche +16 more
TL;DR: In this article, the authors presented a study of Gastroenterology at the University of Toronto and University of Leuven (Belgium) with the aim of identifying the cause of colorectal cancer.
Journal ArticleDOI
Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: a randomised trial.
TL;DR: Mesalazine coated with Eudragit L is a safe, logical alternative to sulphasalazine in patients with active mild to moderate ulcerative colitis and remission rates were 74% and 81% in the two treatment groups respectively.
References
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Journal ArticleDOI
An experiment to determine the active therapeutic moiety of sulphasalazine
TL;DR: It is concluded that the active therapeutic moiety of S.A.S.P. is a function of the parent molecule or of these two principal metabolites of sulphapyridine and 5-aminosalicylic acid.
Journal ArticleDOI
Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype.
TL;DR: Reintroduction of a therapeutic dose of salicylazosulfapyridine was achieved by an initially small dose, which was then gradually increased, and this method could be continued in 26 out of 28 patients who exhibited side effects.
Journal ArticleDOI
Biopsy studies in ulcerative colitis
S. C. Truelove,W. C. D. Richards +1 more
TL;DR: The main object in the present paper is to present the relationships between the clinical state, sigmoidoscopic appearance, and histological findings in serial biopsy studies of the colonic mucosa in ulcerative colitis.
Journal ArticleDOI
Controlled trial of sulphasalazine in maintenance therapy for ulcerative colitis
Journal ArticleDOI
Intensive intravenous treatment of ulcerative colitis.
TL;DR: No long-term benefit was seen in patients with total ulcerative colitis, but half of those with less extensive colitis showed a good to excellent response to treatment, especially in severe attacks.
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An experiment to determine the active therapeutic moiety of sulphasalazine
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