G
Gert Van Assche
Researcher at Katholieke Universiteit Leuven
Publications - 382
Citations - 40893
Gert Van Assche is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Ulcerative colitis & Inflammatory bowel disease. The author has an hindex of 83, co-authored 378 publications receiving 35941 citations. Previous affiliations of Gert Van Assche include University of Toronto & University Health Network.
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Journal ArticleDOI
Vedolizumab as induction and maintenance therapy for ulcerative colitis.
Brian G. Feagan,Paul Rutgeerts,Bruce E. Sands,Stephen B. Hanauer,Jean-Frederic Colombel,Jean-Frederic Colombel,William J. Sandborn,Gert Van Assche,Jeffrey Axler,Hyo-Jong Kim,Silvio Danese,I. Fox,Catherine Milch,Serap Sankoh,Tim Wyant,Jingcan Xu,Asit Parikh +16 more
TL;DR: Vedolizumab was more effective than placebo as induction and maintenance therapy for ulcerative colitis and the frequency of adverse events was similar in the vedolIZumab and placebo groups.
Journal ArticleDOI
Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease.
Filip Baert,Maja Noman,Severine Vermeire,Gert Van Assche,Geert D' Haens,An Carbonez,Paul Rutgeerts +6 more
TL;DR: The development of antibodies against infliximab is associated with an increased risk of infusion reactions and a reduced duration of response to treatment, and concomitant immunosuppressive therapy reduces the magnitude of the immunogenic response.
Journal ArticleDOI
The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis
Gert Van Assche,Axel Dignass,Julián Panés,Laurent Beaugerie,John A. Karagiannis,Mathieu Allez,Thomas Ochsenkühn,Timothy R. Orchard,Gerhard Rogler,Edouard Louis,Limas Kupčinskas,Gerassimos J. Mantzaris,Simon Travis,Eduard F. Stange +13 more
TL;DR: The aim of the Consensus is to promote a European perspective on the management of Crohn's disease and its dilemmas to avoid duplication of effort in the future.
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3rd European Evidence-based Consensus on the Diagnosis and Management of Crohn’s Disease 2016: Part 1: Diagnosis and Medical Management
Fernando Gomollón,Axel Dignass,Vito Annese,Herbert Tilg,Gert Van Assche,James O. Lindsay,Laurent Peyrin-Biroulet,Garret Cullen,Marco Daperno,Torsten Kucharzik,Florian Rieder,Sven Almer,Alessandro Armuzzi,Marcus Harbord,Jost Langhorst,Miquel Sans,Yehuda Chowers,Gionata Fiorino,Pascal Juillerat,Gerassimos J. Mantzaris,Fernando Rizzello,Stephan R. Vavricka,Paolo Gionchetti +22 more
TL;DR: The methodology of the consensus process, and the classification, diagnosis and medical management of active and quiescent Crohn’s disease of this ECCO Consensus are concerns.
Journal ArticleDOI
Second European evidence-based consensus on the diagnosis and management of ulcerative colitis Part 2: Current management
Axel Dignass,James O. Lindsay,Andreas Sturm,Alastair Windsor,Jean-Frederic Colombel,Mathieu Allez,G. D'Haens,André D'Hoore,Gerassimos J. Mantzaris,Gottfried Novacek,Tom Øresland,Walter Reinisch,Miquel Sans,Eduard F. Stange,Severine Vermeire,Simon Travis,Gert Van Assche +16 more
TL;DR: The most widely used index for severe UC remains that of Truelove and Witts3: any patient who has a bloody stool frequency ≥ 6/day and a tachycardia (> 90 bpm), or temperature > 37.8 °C, or anaemia (haemoglobin 30 mm/h) has severe ulcerative colitis (Table 1.3) as mentioned in this paper.