Journal ArticleDOI
Bacterial colonization of percutaneous sutures
Hal G. Bingham,A. G. Gristina +1 more
Reads0
Chats0
TLDR
It is suggested that this mode of growth, in which the colonizing bacteria are enveloped in a copious exopolysaccharide glycocalix, protects the bacteria from host defense factors and accounts for their persistence on the suture surfaces until they are removed with the sutures.Abstract:
The direct electron microscopic examination of 15 sutures and 15 staples removed from 10 healed surgical wounds showed, on the intradermal portions, consistent colonization by bacteria growing in adherent biofilms. This clearly demonstrable bacterial colonization of biomaterials within the wound tract had not resulted in infection or perceptible inflammation in any of the wounds. These bacterial cells were of several morphotypes, including gram-positive cocci, and all specimens yielded cultures of the autochthonous (native) skin bacterium, Staphylococcus epidermidis. The bacteria within the wound tracts were enveloped by extracellular material that appeared on scanning electron microscopy to be a condensed amorphous residue and on transmission electron microscopy to be a fibrous extracellular matrix. We suggest that this mode of growth, in which the colonizing bacteria are enveloped in a copious exopolysaccharide glycocalix, protects the bacteria from host defense factors and accounts for their persistence on the suture surfaces until they are removed with the sutures.read more
Citations
More filters
Journal ArticleDOI
The Effects of Triclosan Impregnated Suture Materials on Colonic Anastomosis
TL;DR: Slowly absorbable and monofilament PDS suture material causes less tissue reaction and inflammatory response compared to the Vicryl suturematerial that is absorbable in the colonic anastomosis line and multifilament.
Journal ArticleDOI
Benefits of cyanoacrylate mesh closure following exploratory laparotomy in horses.
TL;DR: In this article , the benefits of using topical 2-octyl cyanoacrylate (2-OCA) mesh for skin closure of laparotomy incisions were evaluated in horses.
Journal ArticleDOI
Triclosan-coated barbed sutures in elective laparoscopic colorectal cancer surgery: a propensity score matched cohort study
V. Pla-Martí,José Martín-Arévalo,David Moro-Valdezate,Stephanie García-Botello,L Pérez-Santiago,Ana Izquierdo-Moreno,Ernesto Muñoz-Sornosa,Alejandro Espí-Macías +7 more
TL;DR: In this paper , the use of Triclosan-coated barbed sutures (TCBS) was associated with a lower incidence of incisional surgical site infection (SSI) and lower duration of hospital stay compared to standard suture.
References
More filters
Journal ArticleDOI
Bacterial biofilms in nature and disease.
Journal ArticleDOI
Biofilms and Wounds: An Overview of the Evidence
TL;DR: It is hypothesized that because microorganisms attach to any surface, biofilms can be found in all chronic wounds, and it is not the biofilm per se that represents the greatest obstacle to the healing of a chronic wound, but its virulence and pathogenicity.
Journal ArticleDOI
Occlusive dressings: a microbiologic and clinical review.
TL;DR: The microbiology of normal skin and wounds is discussed and the rates of infection reported under both conventional (nonocclusive) dressings and all occlusive dressings are examined, together with cost factors.
Journal ArticleDOI
Bacterial adherence to surgical sutures: can antibacterial-coated sutures reduce the risk of microbial contamination?
Charles E. Edmiston,Gary R. Seabrook,Michael P. Goheen,Candace J. Krepel,Christopher P. Johnson,Brian D. Lewis,Kellie R. Brown,Jonathan B. Towne +7 more
TL;DR: In this paper, the authors used a standardized in vitro microbiologic model to assess bacterial adherence and the antibacterial activity of a triclosan-coated polyglactin 910 (braided) suture against selected Gram-positive and Gram-negative clinical isolates that may infect surgical wounds.
Journal ArticleDOI
Penetration of Rifampin through Staphylococcus epidermidis Biofilms
Zhilan Zheng,Philip S. Stewart +1 more
TL;DR: Rifampin penetrated biofilms formed by Staphylococcus epidermidis but failed to effectively kill the bacteria, as well as observation of antibiotic-affected cells at the distal edge of the biofilm.