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Journal ArticleDOI

Biological Antioxidant Protection against Lipid Peroxidation Damage

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This article is published in The American Journal of Clinical Nutrition.The article was published on 1970-08-01. It has received 73 citations till now. The article focuses on the topics: Lipid metabolism & Lipid peroxidation.

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Journal ArticleDOI

Mitochondrial role in cell aging

TL;DR: The fine structural and biochemical data support the concept that the mitochondria of fixed postmitotic cells may be the site of intrinsic aging because of the attack by free radicals and lipid peroxides originating in the organelles as a by-product of oxygen reduction during respiration.
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Lipofuscin of the retinal pigment epithelium: A review

TL;DR: The recent advances in knowledge of the composition, origin, and possible deleterious effects of RPE cell lipofuscin are reviewed.
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The cooperative interaction between vitamin E and vitamin C in suppression of peroxidation of membrane phospholipids

TL;DR: In order to further investigate the cooperation between ascorbate and vitamin E in suppressing lipid peroxidation, a liposomal system containing polyunsaturated phospholipids was used and the mixture of antioxidants was much more effective than the sum of both vitamins alone.
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Cadmium-induced lipid peroxidation and the status of the antioxidant system in rat tissues.

TL;DR: Results show that Cd induced LPO in the tissues and the condition was partially counteracted by the antioxidant system, suggesting that the production of NADPH by the HMP shunt is required to reduce the oxidative damage.
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Fluorescent products of lipid peroxidation of mitochondria and microsomes.

TL;DR: Liver microsomes and mitochondria and heart sarcosomes from rats fed diets with varying α-tocopherol concentrations and lipid contents were peroxidized over a 6 hr time period and fluorescent molecular damage represented by that accumulated in human heart age pigment by 50 years of age was calculated.