Journal ArticleDOI
Biological Monitoring for Pesticide Exposure
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This article is published in ChemInform.The article was published on 1990-08-07. It has received 49 citations till now. The article focuses on the topics: Pesticide.read more
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Journal ArticleDOI
Analytical methods for biological monitoring of exposure to pesticides: a review
Dana B. Barr,Larry L. Needham +1 more
TL;DR: A review of existing analytical methodology for the biological monitoring of exposure to pesticides is presented in this article, where the authors also present a critical assessment of the existing methodology and explore areas in which more research is needed.
Journal ArticleDOI
Measurement of dialkyl phosphate metabolites of organophosphorus pesticides in human urine using lyophilization with gas chromatography-tandem mass spectrometry and isotope dilution quantification.
Roberto Bravo,Lisa M. Caltabiano,Gayanga Weerasekera,Ralph D. Whitehead,Carolina Fernandez,Larry L. Needham,Asa Bradman,Dana B. Barr +7 more
TL;DR: Use of this method with approximately 1100 urine samples collected from pregnant women and children indicate that the low limits of detection allow this method to be used in general population studies.
Journal ArticleDOI
Biomarkers of human exposure to pesticides
TL;DR: A widely used biochemical biomarker, cholinesterase depression, measures exposure to organophosphorus insecticides as mentioned in this paper, which is used to detect the effects of pesticides before adverse clinical health effects occur.
Journal ArticleDOI
Use of the fluorescent micronucleus assay to detect the genotoxic effects of radiation and arsenic exposure in exfoliated human epithelial cells.
TL;DR: The exfoliated cell micronucleus (MN) assay using fluorescent in situ hybridization (FISH) with a centromeric probe is a rapid method for determining the mechanism of MN formation in epithelial tissues exposed to carcinogenic agents.
Journal ArticleDOI
The influence of skin structure on permeability: an intersite and interspecies comparison with hydrophilic penetrants.
TL;DR: Skin structure was compared with permeability and there was no apparent relationship between skin structure and permeability to the most rapid penetrants, water and ethanol, but there was an 80-times range in follicle area, which correlated with the observed differences in rate of mannitol and paraquat absorption.