Proceedings ArticleDOI
Cancer Cell Procoagulant Activity
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The article was published on 1979-01-01. It has received 15 citations till now. The article focuses on the topics: Cancer cell.read more
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Journal ArticleDOI
Fibrin as a component of the tumor stroma: origins and biological significance
Harold F. Dvorak,Harold F. Dvorak,Donald R. Senger,Donald R. Senger,Ann M. Dvorak,Ann M. Dvorak +5 more
TL;DR: The current status of fibrin's role in the biology of tumor growth is reviewed, considering such important possiblities as a barrier function to the immune response and possible roles in angiogenesis, desmoplasia, and metastasis.
Journal ArticleDOI
Role of plasma, platelets, and endothelial cells in tumor metastasis
TL;DR: Thrombocytopenic agents were effective in every tumor system and with any experimental model of metastasis, indicating that platelets play a role in this process.
Journal ArticleDOI
Disseminated intravascular coagulation and related syndromes: a clinical review.
TL;DR: Only by clearly understanding pathophysiologic interrelationships can the clinician and laboratorian appreciate the divergent and wide clinical spectrum of often confusing clinical and laboratory findings in patients with DIC.
Journal ArticleDOI
Role of nk cells in the antimetastatic effect of anticoagulant drugs
TL;DR: The antimetastatic effects of heparin and PGI2 are dependent on levels of NK activity in the host, and platelet aggregation and fibrin coating of the surface of tumor cells may be among the mechanisms by which hematogenously spread tumor cells are protected from destruction by NK cells.
Journal ArticleDOI
A new procoagulant in acute leukemia.
TL;DR: This study provides the first evidence for a procoagulant other than TF that is associated with leukemic cells, and all the samples except two shortened the recalcification time of normal human plasma.
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Harvey R. Gralnick,Elinor Abrell +1 more