Journal ArticleDOI
Cardiac glycosides and breast cancer.
Björn Stenkvist,Ewert Bengtsson,Olle Eriksson,J. Holmquist,Bo Nordin,S. Westman-Naeser,Gunnar Eklund +6 more
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This article is published in The Lancet.The article was published on 1979-03-10. It has received 142 citations till now. The article focuses on the topics: Breast cancer & Cancer.read more
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Immunogenic Cell Death in Cancer Therapy
TL;DR: It is postulate that ICD constitutes a prominent pathway for the activation of the immune system against cancer, which in turn determines the long-term success of anticancer therapies and its subversion by pathogens.
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Novel therapeutic applications of cardiac glycosides
TL;DR: The increased susceptibility of cancer cells to these compounds supports their potential use as cancer therapies, and the first generation of glycoside-based anticancer drugs are currently in clinical trials.
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Cardiac glycosides as novel cancer therapeutic agents
TL;DR: This review focuses on recent findings on cellular pharmacology of cardiac glycosides as they relate to treatment of human cancer and attempts to explain why these agents have been overlooked in the past.
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Recent advances in drug repositioning for the discovery of new anticancer drugs.
Joong Sup Shim,Jun O. Liu +1 more
TL;DR: In this review, recent successful examples of drug repositioning for anticancer drug discovery from non-cancer drugs will be discussed.
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Cardiotonic steroids on the road to anti-cancer therapy.
Tatjana Mijatovic,Eric Van Quaquebeke,Bruno Delest,Olivier Debeir,Francis Darro,Robert Kiss,Robert Kiss +6 more
TL;DR: The sodium pump structure, function, expression in diverse cancers and its chemical targeting and that of its sub-units are discussed and the potential of chemical modification to reduce the cardiovascular side-effects and improve the anti-cancer activity of new molecules is discussed.