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Journal ArticleDOI

Cellular Events Involved in Middle Ear Fluid Production

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TLDR
The finding that some of these problems in children can become refractory and lead to complications, including chronic granulomatous otitis media and mastoiditis, seems to be a valid clinical observation.
Abstract
Inflammation of the middle ear and mastoid can result in fluid which is serous, mucoid, bloody, purulent or a combination of the above. Middle ear fluid problems are more common in children. That some of these problems in children can become refractory and lead to complications, including chronic granulomatous otitis media and mastoiditis, seems to be a valid clinical observation. This suggests that predisposing underlying factors for middle ear fluid problems and certain forms of chronic inflammatory mastoid disease exist as common denominators for both entities.

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Citations
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Lesions of the Petrous Apex: Diagnosis and Management

TL;DR: The latest diagnostic and management strategies are discussed and an update of some of the more common pathologic entities is provided.
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Eustachian tube obstruction after intranasal challenge with house dust mite

TL;DR: Results show that intranasal challenge with D farinae can provoke immune-mediated nasal obstruction and eustachian tube dysfunction in sensitized subjects.
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Effect of surgical alterations of the tensor veli palatini muscle on eustachian tube function.

TL;DR: Functional ET obstruction was created in 22 rhesus monkeys by surgically altering the tensor veli palatini (TVP) muscle using three different procedures: 1) complete excision of the muscle; 2) transection of the superficial muscle bundle; or 3) transposition of the Muscle tendon medial to the hamular process.
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Eustachian tube function: physiology, pathophysiology, and role of allergy in pathogenesis of otitis media

TL;DR: Future studies are needed to define the role of allergy in the pathophysiology of the Eustachian tube and the pathogenesis of otitis media and Randomized clinical trials will be required to determine the efficacy of the currently popular forms of immunotherapy and allergy control in the prevention of Otitis media.
Journal ArticleDOI

Middle ear mucosa in rats and humans.

TL;DR: The rat seems to be a suitable model for middle ear studies, however, to be able to compare results obtained in different species and/or different laboratories, the areas of the middle ear from which the specimens have been taken must be carefully defined and presented in a standardized manner.
References
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Journal ArticleDOI

Cytochemical demonstration of succinic dehydrogenase by the use of a new p-nitrophenyl substituted ditetrazole.

TL;DR: The new p-nitrophenyl substituted ditetrazole is introduced, which possesses most of the properties of an ideal reagent for histochemical purposes and permits the cytochemical visualization of the sites of enzymic activity in tissue sections from 2-8 µ thick, under aerobic conditions, after a relatively short incubation period.
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A simple ultraviolet spectrophotometric method for the determination of protein.

TL;DR: An ultraviolet spectrophotometric method for the determination of proteins has advantages over other methods in simplicity, rapidity, accuracy, specificity, and sensitivity, but is not useful for thedetermination of protein in urine.
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STUDIES ON INFLAMMATION : II. The Site of Action of Histamine and Serotonin along the Vascular Tree: A Topographic Study

TL;DR: By killing animals at varying intervals after injections, it was found that the carbon particles were slowly removed from the vascular walls by the action of phagocytic cells, and after 10 months there was still enough carbon locally to be recognized by the naked eye.
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