Open AccessJournal Article
Clinical significance of colonic fermentation.
TLDR
The clinical and metabolic consequences of colonic fermentation are reviewed and the potential benefits of short chain fatty acids are investigated.About:
This article is published in The American Journal of Gastroenterology.The article was published on 1990-10-01 and is currently open access. It has received 104 citations till now.read more
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Colonic health: fermentation and short chain fatty acids.
TL;DR: More human studies are now needed on SCFAs, especially, given the diverse nature of carbohydrate substrates and the SCFA patterns resulting from their fermentation, which will be key to the success of dietary recommendations to maximize colonic disease prevention.
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Short-chain Fatty Acids in Control of Body Weight and Insulin Sensitivity
TL;DR: This Review discusses the effects of three SCFA on energy homeostasis and metabolism, as well as how these SCFA can beneficially modulate adipose tissue, skeletal muscle and liver tissue function and the increasing evidence for a potential role of SCFA as metabolic targets to prevent and counteract obesity.
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Adiposity, gut microbiota and faecal short chain fatty acids are linked in adult humans
TL;DR: The results support the hypothesis that colonic fermentation patterns may be altered, leading to different faecal SCFA concentrations in OWOB compared with LN humans, and help determine the role of SCFA in obesity.
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Pathways of acetate, propionate, and butyrate formation by the human fecal microbial flora.
Terry L. Miller,Meyer J. Wolin +1 more
TL;DR: Results with suspensions from subject 2 suggested that some radioactive acetate was formed from the C-3 of glucose by the Bifidobacterium pathway, and the amount of CO2 formed from [1-14C] glucose and acetate labeling patterns obtained with the other 14C precursors indicated that the Entner-Doudoroff, transketolase-transaldolase, and heterolactic pathways were not significant.
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Influence of dietary protein supplements on the formation of bacterial metabolites in the colon.
Benny Geypens,D Claus,Pieter Evenepoel,Martin Hiele,Bart Maes,Marc Peeters,Paul Rutgeerts,Yvo Ghoos +7 more
TL;DR: An increase in dietary protein leads to altered products formation by colonic metabolism, mainly reflected by an increase in faecal ammonia,Faecal volatile S substances, and urinary p-cresol.