E
Elena M. Comelli
Researcher at University of Toronto
Publications - 77
Citations - 3155
Elena M. Comelli is an academic researcher from University of Toronto. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 19, co-authored 53 publications receiving 2346 citations. Previous affiliations of Elena M. Comelli include Brock University.
Papers
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Journal ArticleDOI
Intestinal Microbiota in Patients With Nonalcoholic Fatty Liver Disease
Marialena Mouzaki,Elena M. Comelli,Bianca M. Arendt,Julia Bonengel,Scott Fung,Scott Fung,Sandra Fischer,Sandra Fischer,Ian D. McGilvray,Ian D. McGilvray,Johane P. Allard,Johane P. Allard +11 more
TL;DR: There continued to be a significant association between the presence of NASH and lower percentage Bacteroidetes even after adjusting for these variables and body mass index and dietary fat intake.
Journal ArticleDOI
Adiposity, gut microbiota and faecal short chain fatty acids are linked in adult humans
TL;DR: The results support the hypothesis that colonic fermentation patterns may be altered, leading to different faecal SCFA concentrations in OWOB compared with LN humans, and help determine the role of SCFA in obesity.
Journal Article
Intestinal Microbiota in Patients with Non-Alcoholic Fatty Liver Disease
Marialena Mouzaki,Elena M. Comelli,Bianca M. Arendt,Julia Bonengel,Scott Fung,Sandra Fischer,Ian D. McGilvray,Johane P. Allard +7 more
TL;DR: In this article, a prospective, cross-sectional study was aimed at identifying differences in the intestinal microbiota (IM) composition of patients with non-alcoholic fatty liver disease (NAFLD) and living liver donors as healthy controls (HC).
Journal ArticleDOI
Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease.
Marialena Mouzaki,Alice Y. Wang,Robert H. J. Bandsma,Elena M. Comelli,Bianca M. Arendt,Ling Zhang,Scott Fung,Scott Fung,Sandra Fischer,Sandra Fischer,Ian G. McGilvray,Ian G. McGilvray,Johane P. Allard,Johane P. Allard +13 more
TL;DR: In adults with NAFLD, dysbiosis is associated with altered BA homeostasis, which renders them at increased risk of hepatic injury.
Journal ArticleDOI
Altered hepatic gene expression in nonalcoholic fatty liver disease is associated with lower hepatic n‐3 and n‐6 polyunsaturated fatty acids
Bianca M. Arendt,Elena M. Comelli,David W.L. Ma,Wendy Lou,Anastasia Teterina,TaeHyung Kim,Scott Fung,David Wong,Ian D. McGilvray,Sandra Fischer,Johane P. Allard +10 more
TL;DR: Well‐defined subjects with either healthy liver, SS, or NASH showed distinct hepatic gene expression profiles including genes involved in unsaturated FA metabolism, and in patients with NASH, hepatic PUFAs were lower and associations with gene expression were different compared to SS.