Open AccessJournal Article
Comparative performance for immediate hypersensitivity skin testing using two skin prick test devices.
TLDR
The two methods are similar with respect to determining the immediate hypersensitivity, but the Multi-Test is better accepted by children.Abstract:
Fifty-five patients were skin-tested by Multi-Test (M) and needle prick test (NPT) to compare the reproducibility of the methods. We used 6 allergenic extracts: Dermatophagoides pteronyssinus, Dermatophagoides farinae, dog epithelium, cat pelt, American cockroach and mixed molds. A glycerosaline and a positive control (histamine 1 mg/ml) were performed in both methods. Statistically significant differences in histamine and Dermatophagoides farinae wheal reactions between the two methods (M > NPT) were found, with no differences with the other allergenic extracts. We concluded that the two methods are similar with respect to determining the immediate hypersensitivity, but the Multi-Test is better accepted by children.read more
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The Lancet Weight Determines Wheal Diameter in Response to Skin Prick Testing with Histamine.
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TL;DR: Children with polysensitization and mould sensitization were more likely to show a large significant histamine response, whereas children with passive smoke exposure, showed a diminished skin reactivity to histamine.
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Comparison of the Multi-Test II and ComforTen allergy skin test devices.
TL;DR: Multi-Test II had notably lower CV, greater wheal size, and higher sensitivity but similar specificity to ComforTen, and had superior performance at both 3- and 5-mm wheal cutoffs.