Journal ArticleDOI
Comparison of arterial spin-labeling techniques and dynamic susceptibility-weighted contrast-enhanced MRI in perfusion imaging of normal brain tissue.
Marc-André Weber,Matthias Günther,Matthias P. Lichy,Stefan Delorme,Andre Bongers,Christoph Thilmann,Marco Essig,Ivan Zuna,Lothar R. Schad,Jürgen Debus,Heinz Peter Schlemmer +10 more
TLDR
Both ASL and DSC EPI MRI yield highly comparable perfusion values in normal brain tissue, which correlated well by calculating Pearson's correlation coefficients and remained unchanged after stereotactic radiosurgery.Abstract:
Objectives:To evaluate relative cerebral blood flow (rCBF) in normal brain tissue using arterial spin-labeling (ASL) methods and first-pass dynamic susceptibility-weighted contrast-enhanced (DSC) magnetic resonance imaging (MRI).Methods:Sixty-two patients with brain metastases were examined on a 1.5read more
Citations
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Journal ArticleDOI
Arterial spin-labeling in routine clinical practice, part 1: technique and artifacts.
A. R. Deibler,Jeffrey M. Pollock,Robert A. Kraft,Huan Tan,Jonathan H. Burdette,Joseph A. Maldjian +5 more
TL;DR: The experience with a heterogeneous collection of ASL perfusion cases with an emphasis on methodology and common artifacts encountered with the technique is described to help avoid pitfalls in the interpretation of CBF maps.
Journal ArticleDOI
Perfusion imaging using arterial spin labeling.
TL;DR: In this review, the multiple facets of this powerful yet difficult technique are discussed, different implementations are compared, the theoretical background is summarized, and potential applications of various implementations in research as well as in the daily clinical routine are proposed.
Journal ArticleDOI
Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial spin labeled perfusion MRI
Guoqiang Yu,Thomas F. Floyd,Turgut Durduran,Chao Zhou,Jiongjiong Wang,John A. Detre,Arjun G. Yodh +6 more
TL;DR: The results provide much needed quantitative blood flow validation of the diffuse optical correlation method in humans.
Journal ArticleDOI
Diagnostic performance of spectroscopic and perfusion MRI for distinction of brain tumors
Marc-André Weber,S. Zoubaa,M. Schlieter,E. Jüttler,Hagen B. Huttner,K. Geletneky,C. Ittrich,Matthias P. Lichy,A. Kroll,Jürgen Debus,Frederik Giesel,Marius Hartmann,Marco Essig +12 more
TL;DR: Perfusion MRI is predictive in distinguishing glioblastomas from metastases, CNS lymphomas and other gliomas vs MRI and magnetic resonance spectroscopy.
Journal ArticleDOI
Arterial spin-labeling in routine clinical practice, part 3: hyperperfusion patterns.
A. R. Deibler,Jeffrey M. Pollock,Robert A. Kraft,Huan Tan,Jonathan H. Burdette,Joseph A. Maldjian +5 more
TL;DR: Arterial spin-labeled ASL perfusion imaging can be implemented successfully into a routine clinical neuroimaging protocol and can accurately demonstrate alterations in brain perfusion.
References
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Journal ArticleDOI
High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part I: Mathematical approach and statistical analysis
TL;DR: Comparisons showed that a nonparametric deconvolution technique (singular value decomposition) allows estimation of flow relatively independent of underlying vascular structure and volume even at low signal‐to‐noise ratio associated with pixel‐by‐pixel deconvolved.
Journal ArticleDOI
Quantification of relative cerebral blood flow change by flow-sensitive alternating inversion recovery (FAIR) technique: application to functional mapping.
TL;DR: The FAIR technique has been successfully applied to functional brain mapping studies in humans during finger opposition movements and is capable of generating microvascular‐based functional maps.
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Reduced Transit-Time Sensitivity in Noninvasive Magnetic Resonance Imaging of Human Cerebral Blood Flow
David C. Alsop,John A. Detre +1 more
TL;DR: A theoretical framework and experimental methods to more accurately account for transit effects in quantitative human perfusion imaging using endogenous magnetic resonance imaging (MRI) contrast are presented and a novel method for measuring T1, which is fast, insensitive to contamination by cerebrospinal fluid, and compatible with the application of magnetization transfer saturation is presented.
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Quantitative imaging of perfusion using a single subtraction (QUIPSS and QUIPSS II)
TL;DR: Two modifications of pulsed ASL (QUIPSS and QUIPSS II) are introduced that avoid this problem by applying additional saturation pulses to control the time duration of the tagged bolus, rendering the technique relatively insensitive to transit delays and improving the quantitation of perfusion.
Journal ArticleDOI
A multi-institutional experience with stereotactic radiosurgery for solitary brain metastasis
John C. Flickinger,Douglas Kondziolka,L. Dade Lunsford,Robert J. Coffey,Michael L. Goodman,Edward G. Shaw,W. Robert Hudgins,Richard L. Weiner,Griffith R. Harsh,Penny K. Sneed,David A. Larson +10 more
TL;DR: Radiosurgery is effective in controlling solitary brain metastases with low morbidity and further study is needed to better define optimum treatment parameters for radiosurgery.