Journal ArticleDOI
Congenital defects in guinea pigs: fetal resorptions, abortions, and malformations following induced hyperthermia during early gestation.
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This article is published in Teratology.The article was published on 1969-11-01. It has received 115 citations till now.read more
Citations
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Maternal hyperthermia and the risk for neural tube defects in offspring: systematic review and meta-analysis.
TL;DR: Maternal hyperthermia in early pregnancy is associated with increased risk for neural tube defects and may be a human teratogen.
Journal ArticleDOI
Hyperthermia as a teratogen: A review of experimental studies and their clinical significance
TL;DR: Hyperthermia appears to be capable of causing congenital defects in all species and may act alone or synergistically with other agents.
Journal ArticleDOI
Current status of research on biophysical effects of ultrasound.
TL;DR: This paper provides an overview of trends in research into nonthermal mechanisms as a preliminary to the next WFUMB Symposium on Safety of Medical Ultrasound when this subject will be examined in detail by a select group of international experts.
Journal ArticleDOI
Teratogen update: gestational effects of maternal hyperthermia due to febrile illnesses and resultant patterns of defects in humans.
TL;DR: By reviewing the effects of hyperthermia in experimental animals, as well as malformative and protective mechanisms of teratogenesis, this work has attempted to understand the results of humanHyperthermia teratogenic effects.
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Review: Hyperthermia and fever during pregnancy.
TL;DR: Suggested future human studies include problems of CNS function after exposure to influenza and fever, including mental retardation, schizophrenia, autism, and cerebral palsy.
References
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Journal ArticleDOI
Prenatal growth in guinea‐pigs with special reference to environmental factors affecting weight at birth
Journal ArticleDOI
Congenital malformations in the rat following induced hyperthermia during gestation.
TL;DR: Hyperthermia induced in pregnant rats by exposures for 40 to 60 minutes in an incubator that raised deep body temperatures produced increased fetal resorptions, retardation of growth, and a number of development defects.
Journal ArticleDOI
Uterine Vascular Clamping: New Procedure for the Study of Congenital Malformations
Robert L. Brent,John B. Franklin +1 more
TL;DR: Clamping the uterine blood vessels of the rat on the 9th day of gestation for � to 3 hours resulted in fetal death, growth retardation, and severe congenital malformations.