Journal ArticleDOI
Crohn's disease of the vulva.
TLDR
It is concluded that Crohn's disease is not confined to the gastrointestinal tract, and that early lesions of the disease within theintestinal tract are submucosal rather than mucosal.Abstract:
Three patients with Crohn’s disease primarily involving the large intestine had unusual abscesses of the vulvar area. At biopsy, the abscesses had classic features of the primary disease and were clearly separated from the intestinal tract. There was no fistula in the anal canal, and the perineum between the vulvar abscess and the anus was normal. One of the patients also had an early lesion of Crohn’s disease in the sigmoid. The lesion appeared as a small erythematous spot without ulceration. Biopsy revealed a typical granuloma under an intact mucosa. It is concluded that Crohn’s disease is not confined to the gastrointestinal tract, and that early lesions of the disease within the gastrointestinal tract are submucosal rather than mucosal.read more
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Journal ArticleDOI
Cutaneous Crohn's disease in children
Tanusin Ploysangam,James E. Heubi,Drore Eisen,William F. Balistreri,Anne W. Lucky,Anne W. Lucky +5 more
TL;DR: In this article, the authors describe five children with cutaneous Crohn's disease and review the literature for clinical features and laboratory data, showing that the cutaneous manifestations are rarely a presenting sign.
Journal ArticleDOI
Metastatic Crohn's disease: a review.
TL;DR: The most relevant characteristics of this disease are reviewed, in order to increase awareness and to avoid delay in diagnosis and improve management of the whole CD complex.
Journal ArticleDOI
Crohn's disease of the vulva.
Maximilien Barret,Vincent de Parades,Maxime Battistella,Harry Sokol,Nicolas Lemarchand,Philippe Marteau +5 more
TL;DR: Treatment options include oral prolonged courses of metronidazole and systemic immunosuppressive therapy such as corticosteroids and azathioprine, with promising data published on the efficacy of infliximab.
Journal ArticleDOI
Granulomatous myositis and myopathy associated with crohn's colitis.
TL;DR: A 44-year-old man admitted to the hospital with a six-week history of non-bloody diarrhea, crampy abdominal pain, arthralgia, fever and a 4.5-kg weight loss is diagnosed with extraintestinal complications of inflammatory bowel disease.
Journal ArticleDOI
Granulomatous lymphangitis of the scrotum and penis. Report of a case and review of the literature of genital swelling with sarcoidal granulomatous inflammation.
TL;DR: Acquired lymphedema of the genitalia is a rare childhood presentation and is more common in elderly individuals secondary to pelvic/abdomenal malignancy or its therapy or worldwide due to filariasis.