Disinction of enantiomers by NMR spectroscopy using chiral orienting media

TLDR: A review of the techniques being developed for enantiomeric differentiation by virtue of chiral alignment media and their induction of anisotropic NMR parameters like residual dipolar couplings can be found in this article.

Abstract: NMR spectroscopy is a very important analytical tool in modern organic and inorganic chemistry. Next to the identification of molecules and their structure determination, it is also used for the distinction of enantiomers and the measurement of enantiomeric purity. This article gives a brief review of the techniques being developed for enantiomeric differentiation by virtue of chiral alignment media and their induction of enantiomerically dependent anisotropic NMR parameters like residual dipolar couplings. An overview of existing chiral alignment media, a brief introduction into the basic theory and measurement of the various anisotropic parameters, and several example applications are given.