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Disorders of glucose metabolism in sleep apnea

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TLDR
The available data suggest that sleep apnea is independently associated with altered glucose metabolism and may predispose to the eventual development of Type 2 diabetes mellitus, and the cause-and-effect relationship remains to be determined.
Abstract
Sleep is a complex behavioral state that occupies one-third of the human life span. Although viewed as a passive condition, sleep is a highly active and dynamic process. The sleep-related decrease ...

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Citations
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Journal ArticleDOI

The Epidemiology of Adult Obstructive Sleep Apnea

TL;DR: Some of the epidemiologic aspects of obstructive sleep apnea in adults are reviewed, namely, loud snoring, observed apneas, and daytime sleepiness, to help identify those in need of further diagnostic evaluation.
Journal ArticleDOI

Sleep Apnea and Cardiovascular Disease

TL;DR: The American Heart Association/American College of Cardiology Scientific Statement on Sleep Apnea and Cardiovascular Disease as discussed by the authors highlights concepts and evidence important to understanding the interactions between sleep apnea and cardiovascular disease, with particular attention to more recent advances in patient-oriented research.
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Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities

TL;DR: Large-scale collaborative studies of carefully defined patient populations with obstructive sleep apnoea syndrome, adequately controlled for potential confounders, are needed and research priorities to identify the underlying mechanisms involved are proposed, with a view to identifying novel therapeutic strategies.
References
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Journal ArticleDOI

The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults

TL;DR: The prevalence of undiagnosed sleep-disordered breathing is high among men and is much higher than previously suspected among women, and is associated with daytime hypersomnolence.
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Prevalence and Trends in Obesity Among US Adults, 1999-2000

TL;DR: The increases in the prevalences of obesity and overweight previously observed continued in 1999-2000, and increases occurred for both men and women in all age groups and for non-Hispanic whites, non- Hispanic blacks, and Mexican Americans.
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Global Burden of Diabetes, 1995–2025: Prevalence, numerical estimates, and projections

TL;DR: This report supports earlier predictions of the epidemic nature of diabetes in the world during the first quarter of the 21st century and provides a provisional picture of the characteristics of the diabetes epidemic.
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Global and societal implications of the diabetes epidemic

TL;DR: The prevention of diabetes and control of its micro- and macrovascular complications will require an integrated, international approach if the authors are to see significant reduction in the huge premature morbidity and mortality it causes.
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