Journal ArticleDOI
Effect of ADH, aldosterone, ouabain, and amiloride on toad bladder epithelial cells
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This article is published in American Journal of Physiology.The article was published on 1972-05-01. It has received 94 citations till now. The article focuses on the topics: Amiloride & Ouabain.read more
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Journal ArticleDOI
The mammalian urinary bladderan accommodating organ
TL;DR: Urinary bladders are found in the amphibia, chelonian reptiles and mammals and in these orders liquid urine is stored in the bladder and eliminated at intervals from the body by micturation.
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Subcellular mechanisms in the action of adrenal steroids.
TL;DR: Understanding of receptor mechanisms, albeit incomplete, provides an explanation of steroid specificity and overlapping physiologic effects and enables us to design new and more potent steroid antagonists and to rationalize resistance or sensitivity of tumor cells to specific steroids.
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Amiloride directly inhibits the Na,K-ATPase activity of rabbit kidney proximal tubules
TL;DR: Amiloride inhibited the ouabain-sensitive rate of oxygen consumption (QO2) of a suspension of rabbit intact proximal tubules in the presence of different concentrations of extracellular sodium.
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The mechanism of Na+ transport by rabbit urinary bladder.
TL;DR: The resulting model of Na+ transport in “tight” epithelia contains an amiloride-inhibited and Ca++- inhibited conductance pathway for Na+ entry; the basolateral membrane contains a Na+−K+-activated ATPase that extrudes Na+; intracellular (Na+) may exert negative feedback on apical membrane conductance; and aldosterone acts to stimulate Na+.
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ATP and the Regulation of Renal Cell Function
TL;DR: This review is directed toward aspects involving the metabolic support of the renal sodium pump, and several questions related to this synthesis will be considered, including what are the relative contributions to ATP synthesis from the heterogeneous segments of the kidney.