Journal ArticleDOI
Effect of inhibitors of sodium transport on bile formation in the rabbit.
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This article is published in American Journal of Physiology.The article was published on 1970-08-01. It has received 152 citations till now. The article focuses on the topics: Sodium.read more
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Effect of ursodeoxycholate on the bile flow in the rat.
Kenichi Kitani,Setsuko Kanai +1 more
TL;DR: The results appear to be most easily explained by the thesis that there is a fraction of bile independent of bille salt excretion but dependent on the bile salt concentration in the hepatocyte.
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Effects of chlorpromazine hydrochloride and its metabolites on Mg2+- and Na+,K+-ATPase activities of canalicular-enriched rat liver plasma membranes
Alan M. Samuels,Martin C. Carey +1 more
TL;DR: The results suggest that the degree of cholestasis may well be influenced by the extent of the conversion of the drug to its more active (free radical) or minimally active (sulfoxide) metabolites and by the local environment of the canalicular membrane.
Journal ArticleDOI
Relationship between bile flow and Na+, K+-adenosinetriphosphatase in liver plasma membranes enriched in bile canaliculi.
Jürg Reichen,Gustav Paumgartner +1 more
TL;DR: Findings support the hypothesis that a fraction of bile flow is related to Na+,K+-ATPase activity and canalicular Na+ transport.
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Alteration of Bile Canalicular Enzymes in Cholestasis. A POSSIBLE CAUSE OF BILE SECRETORY FAILURE
Francis R. Simon,Irwin M. Arias +1 more
TL;DR: Alterations in specific canalicular enzymes in two forms of cholestasis suggest that these changes may be involved in the pathogenesis of bile secretory failure, or may result from cholESTasis.