Mechanisms and control of secretion of bile water and electrolytes.
S. Erlinger,D. Dhumeaux +1 more
Reads0
Chats0
About:
This article is published in Gastroenterology.The article was published on 1974-02-01 and is currently open access. It has received 161 citations till now.read more
Citations
More filters
Journal ArticleDOI
Hypercholeresis induced by ursodeoxycholic acid and 7-ketolithocholic acid in the rat: possible role of bicarbonate transport.
TL;DR: It is suggested that ursodeoxycholate and 7-ketolithocholate are more potent choleretics than taurocholate; both compounds increase canalicular bicarbonate secretion.
Journal ArticleDOI
Physiology of bile secretion.
TL;DR: The aim of this revision was to set the bases for other reviews in this series that will be devoted to specific issues related with biliary physiology and pathology by summarizes recent data on the molecular determinants of this primary bile formation.
Journal ArticleDOI
Studies of relationship among bile flow, liver plasma membrane NaK-ATPase, and membrane microviscosity in the rat.
TL;DR: It is indicated that LPM fluidity correlates with NaK-ATPase activity and may influence the activity of this enzyme, however, the nature of the role of LPM Na K(m) for ATP in bile secretion is uncertain and needs further study.
Journal ArticleDOI
Bile salts and their importance for drug absorption.
TL;DR: There is a positive effect on bioavailability when bile is present in the gastro-intestinal tract, independent of the formulation systems, e.g. suspensions, solutions, cyclodextrin complexes or lipid based formulations, but a few exceptions have also been reported.
Journal ArticleDOI
Mechanisms of Hepatic Bile Formation
TL;DR: It should be evident from this review of recent investigations that the authors are still very far from a consistent description of bile formation, much less a satisfactory understanding of the actual mechanisms of solute transport, so the term active transport in the present context should be thought of in its general thermodynamic sense rather than as denoting any particular transport mechanism.
References
More filters
Journal ArticleDOI
Enzymatic basis for active transport of na+ and k+ across cell membrane.
TL;DR: Afhnity for Monovalent Cations and Quantitative Relation between Effect of Na+ + K+ on Enzyme System and Active Transport in Intact Cell.
Journal ArticleDOI
The mechanism of pancreatic secretion
W. M. Bayliss,Ernest H. Starling +1 more
TL;DR: The injection of acid into the duodenum and jejunum results in the secretion of pancreatic secretion of secretin, which is responsible for the normal mechanism and action of the nervous system of the organism.
Journal ArticleDOI
Standing-Gradient Osmotic Flow A mechanism for coupling of water and solute transport in epithelia
TL;DR: The results suggest that water-to-solute coupling in epithelia is due to the ultrastructural geometry of the transport route, and a standing-gradient system can yield hypertonic fluids whose osmolarities are virtually independent of transport rate over a wide range.
Journal ArticleDOI
Dissolution of cholesterol gallstones by chenodeoxycholic acid.
TL;DR: Chenodeoxycholic acid may offer medical treatment for cholesterol cholelithiasis in man and the ratio of bile acids and lecithin to cholesterol in bile increased in all patients.
Journal ArticleDOI
Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions
TL;DR: Two hepatic cytoplasmic protein fractions, designated Y and Z, which bind sulfobromophthalein (BSP), bilirubin, and other organic anions, have been separated by G75 Sephadex gel filtration and appear to be important in the transfer of Organic anions from plasma into the liver.