Journal ArticleDOI
Effect of ouabain on cochlear potentials and endolymph composition in guinea pigs.
T. Konishi,M. Mendelsohn +1 more
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The effect of ouabain on cochlear potentials and endolymph composition was studied in guinea pigs, and lowering the concentration of sodium in the perilymph minimized the action of oUabain.Abstract:
The effect of ouabain on cochlear potentials and endolymph composition was studied in guinea pigs. Introduction of ouabain into the perilymphatic space resulted in a serious depression of cochlear ...read more
Citations
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Journal ArticleDOI
Ion transport mechanisms responsible for K+ secretion and the transepithelial voltage across marginal cells of stria vascularis in vitro.
TL;DR: Observed observations are incompatible with a model for the generation of the endocochlear potential which ascribes the entire potential to the strial marginal cells and for a cell model proposed to explain K+.
Journal ArticleDOI
Distribution of immunoreactive Na+,K+-ATPase in gerbil cochlea.
Bradley A. Schulte,Joe C. Adams +1 more
TL;DR: The distribution of Na+,K+-ATPase was mapped in cochleas of mature gerbils with normal hearing, using a specific and sensitive immunocytochemical method, and three different populations of cells lying in the inferior portion of the spiral ligament and at the medial and lateral border of the scala vestibuli just superior to the attachment of Reissner's membrane were detected.
Journal ArticleDOI
Ion Transport in Guinea Pig Cochlea:I. Potassium and Sodium Transport
TL;DR: The scala vestibuli and/or tympani in anesthetized guinea pigs was perfused with artificial perilymph containing 42K and 22Na for periods ranging from 5 to 60 minutes to result in appreciable changes in electrical responses.
Journal ArticleDOI
Comparison of ion transport mechanisms between vestibular dark cells and strial marginal cells.
TL;DR: Evidence is collected that ion transport mechanisms and their regulation are similar in vestibular dark and strial marginal cells and the present review compiles evidence in support of this hypothesis.
Journal ArticleDOI
A study of the electrochemistry and osmotic relationships of the cochlear fluids in the neonatal rat at the time of the development of the endocochlear potential
S. K. Bosher,R. L. Warren +1 more
TL;DR: Changes in the endocochlear potential between the 8th and 18th days after birth were investigated in the rat and the potential was low but its magnitude increased rapidly between the 11th and 16th day.
References
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Journal ArticleDOI
Enzymatic basis for active transport of na+ and k+ across cell membrane.
TL;DR: Afhnity for Monovalent Cations and Quantitative Relation between Effect of Na+ + K+ on Enzyme System and Active Transport in Intact Cell.
Journal Article
The action of cardiac glycosides on ion movements
TL;DR: It is difficult to summarise when so much that has been said is tentative but it is probably fair to state that it is doubtful whether therapeutic doses of cardiac glycosides cause appreciable lowering of the internal potassium concentration.
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The electrolytes of the labyrinthine fluids.
Journal ArticleDOI
The Space‐Time Pattern of the Cochlear Microphonics (Guinea Pig), as Recorded by Differential Electrodes
I. Tasaki,H. Davis,J.-P. Legouix +2 more
TL;DR: In this article, pairs of very small electrodes were placed in two or more turns of the cochlea of the guinea pig and the outputs of the second, third, and fourth turns were compared with that of the first turn with respect to both amplitude and phase as a function of frequency.
Journal ArticleDOI
Effect of Anoxia on Cochlear Potentials
TL;DR: For the brief occlusion durations, the amplitudes of all potentials except cochlear microphonics became greater than normal soon after the blood supply returned, and even for the longer anoxic intervals, the summating potential and the endocochlear potential exhibited super‐normality during the recovery process.