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Journal ArticleDOI

Endoscopic ultrasound as a first test for diagnosis and staging of lung cancer: a prospective study.

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TLDR
Endoscopic ultrasound-guided fine needle aspiration as a first test (after CT) has high diagnostic yield and accuracy for detecting lung cancer metastases to the mediastinum and distant sites and thus avoids thoracotomy.
Abstract
Rationale: Multiple tests are required for the management of lung cancer.Objectives: Endoscopic ultrasound–guided fine needle aspiration (EUS-FNA) was evaluated as a single test for the diagnosis and staging (thoracic and extrathoracic) of lung cancer.Methods: Consecutive subjects with computed tomography (CT) findings of a lung mass were enrolled for EUS and results were compared with those from CT and positron emission tomography scans.Results: Of 113 subjects with lung cancer, EUS was performed as a first test (after CT scan) for diagnosis in 93 (82%) of them. EUS-FNA established tissue diagnosis in 70% of cases. EUS-FNA, CT, and positron emission tomography detected metastases to the mediastinal lymph nodes with accuracies of 93, 81, and 83%, respectively. EUS-FNA was significantly better than CT at detecting distant metastases (accuracies of 97 and 89%, respectively; p = 0.02). Metastases to lymph nodes at the celiac axis (CLNs) were observed in 11% of cases. The diagnostic yields of EUS-FNA and CT f...

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Citations
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Journal ArticleDOI

Endoscopic ultrasound reduces surgical mediastinal staging in lung cancer: a randomized trial.

TL;DR: EUS-FNA reduces the need for surgical staging procedures in patients with (suspected) lung cancer in whom a mediastinal exploration is needed, and the rate of surgical staging interventions was low.
BookDOI

Principles and practice of interventional pulmonology

Armin Ernst, +1 more
TL;DR: This chapter discusses the principles and practice of interventional pulmonology as well as the practical applications of these principles in clinical practice.
Journal ArticleDOI

Transbronchial vs Transesophageal Needle Aspiration Using an Ultrasound Bronchoscope for the Diagnosis of Mediastinal Lesions: A Randomized Study

TL;DR: In this paper, the authors compared the tolerance, efficacy, and safety of endobronchial ultrasound-guided transbronchiial needle aspiration (EBUS-TBNA) with transesophageal endoscopic ultrasoundguided fine-needle aspiration (EUS-FNA) for pathologic diagnosis of lesions accessible by both procedures.
Journal ArticleDOI

Transoesophageal needle aspiration using a convex probe ultrasonic bronchoscope.

TL;DR: This study evaluated the feasibility and the additional role of transoesophageal fine needle aspiration using a convex probe ultrasonic bronchoscope (EUS‐B‐FNA) and found it helpful when combined with bronchoscopic procedures.
References
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Journal ArticleDOI

Revisions in the International System for Staging Lung Cancer

TL;DR: Analysis of a collected database representing all clinical, surgical-pathologic, and follow-up information for 5,319 patients treated for primary lung cancer confirmed the validity of the TNM and stage grouping classification schema.
Journal ArticleDOI

Cancer statistics, 1998

TL;DR: The Surveillance Research Program of the American Cancer Society's Department of Epidemiology and Surveillance reports its 32nd annual compilation of cancer incidence, mortality, and survival data for the United States and around the world.
Journal ArticleDOI

Noninvasive Staging of Non-small Cell Lung Cancer*: A Review of the Current Evidence

TL;DR: PET scanning is more accurate than CT scanning or EUS for detecting mediastinal metastases and the NPVs of the clinical evaluations for brain, abdominal, and bone metastases are > or = 90%, suggesting that routinely imaging asymptomatic lung cancer patients may not be necessary.
Journal ArticleDOI

Metastases from non-small cell lung cancer: mediastinal staging in the 1990s--meta-analytic comparison of PET and CT.

TL;DR: pooled point estimates of diagnostic performance and summary ROC curves indicated that PET was significantly more accurate than CT for demonstration of nodal metastases (P < .001), and PET is superior to CT for mediastinal staging of non-small cell lung cancer, independent of performance index or clinical context of PET imaging.
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What is the most efficient diagnostic test to determine metastasis in lung cancer?

EUS-FNA as a first test (after CT) has high diagnostic yield and accuracy for detecting lung cancer metastases to the mediastinum and distant sites.