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Journal ArticleDOI

Enhanced extraction of rebaudioside-A: Experimental, response surface optimization and prediction using artificial neural network

TLDR
In this article, enhanced Reb-A extraction using water, a green solvent, which is a good alternative to organic solvents, was performed in broad ranges of extraction time (15-75min), leaves to water ratio (2-5%, g/mL) and temperature (50-80°C).
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This article is published in Industrial Crops and Products.The article was published on 2015-03-01. It has received 29 citations till now. The article focuses on the topics: Extraction (chemistry) & Central composite design.

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Citations
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Optimization of microwave-assisted extraction of total extract, stevioside and rebaudioside-A from Stevia rebaudiana (Bertoni) leaves, using response surface methodology (RSM) and artificial neural network (ANN) modelling.

TL;DR: Stevia rebaudiana (Bertoni) consists of stevioside and rebaudioside-A (Reb-A), and response surface methodology (RSM) and artificial neural network (ANN) modelling are compared for their estimation and predictive capabilities in building effective models with maximum responses.
Journal ArticleDOI

Microwave assisted extraction of essential oil from the leaves of Palmarosa: Multi-response optimization and predictive modelling

TL;DR: In this article, the essential oil from the leaves of Cymbopogon martinii was extracted for maximization of yield of oil, yield of geraniol and zone of inhibition (ZOI) as responses.
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Optimization of supercritical fluid extraction of steviol glycosides and total phenolic content from Stevia rebaudiana (Bertoni) leaves using response surface methodology and artificial neural network modeling

TL;DR: In this article, a supercritical fluid extraction (SFE) process was optimized by employing a 5-level-3-factor central composite design to achieve maximum target response values for total extract yield, steviol glycosides (SGs), rebaudioside-A (Reb-A), and total phenolic content.
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Meeting the challenge of stevioside production in the hairy roots of Stevia rebaudiana by probing the underlying process

TL;DR: These findings elucidated the decisive role of UGT85C2 in combination with photosynthetic proficiency of the studied hairy root cultures in regulating the biosynthetic pathway of S. rebaudiana.
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Steviol glycosides and polyphenols extraction from Stevia rebaudiana Bertoni leaves using maceration, microwave-, and ultrasound-assisted techniques

TL;DR: Optimization of steviol glycosides and polyphenols extraction from stevia leaves for maceration, microwave assisted (MAE) and ultrasound assisted (UAE) techniques were performed by investigating th....
References
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Book

RSM Simplified: Optimizing Processes Using Response Surface Methods for Design of Experiments

TL;DR: In this paper, the Beauty of Response Surface Methods (BMSM) is used to find the sweet spot for multiple responses in response surface methods (surface methods) and RSM is applied to Mixtures.
Reference BookDOI

Stevia: the genus Stevia.

TL;DR: This comprehensive volume provides reviews on the botany, ethnobotany, and chemical constituents of the genus Stevia and examines the chemical synthesis of such compounds as steviol and stevioside.
Journal ArticleDOI

Sugar-sweetened soft drinks, obesity, and type 2 diabetes.

TL;DR: This study provides additional evidence that excess calories from sugarsweetened soft drinks are responsible for the increasing prevalence of obesity among adults and also implicates sugarsweetening soft drinks as a cause of type 2 diabetes.
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Sugary drinks in the pathogenesis of obesity and cardiovascular diseases

TL;DR: There is considerable evidence that fructose, rather than glucose, is the more damaging sugar component in terms of cardiovascular risk, and this review focuses on the potential role of sugar drinks, particularly the fructose component, in the pathogenesis of obesity and cardiovascular diseases.
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