Journal ArticleDOI
Enlarged synaptic vesicles as an early sign of secondary degeneration in the optic nerve terminals of the pigeon.
TLDR
The conclusion seems warranted that the ballooning of synaptic vesicles is an early sign of terminal degeneration, it appears to precede vesicular disintegration.Abstract:
The terminal degeneration of retino-tectal fibres was studied electron microscopically in the pigeon Synaptic vesicles seem to undergo systematic changes which can best be observed in aldehyde-fixed material. Initially (i.e. within 12-24 h) the vesicles begin to swell. The enlargement is clearly visible after 4 days (40 % increase in diameter) and reaches a maximum at 14 days (100% increase). At the latter stage, the enlargement is almost invariably associated with the well known opacity of degenerating terminals. In contrast, normal control tissue contains nerve endings with only a few enlarged and no ballooning vesicles. The conclusion seems warranted that the ballooning of synaptic vesicles is an early sign of terminal degeneration, it appears to precede vesicular disintegration.read more
Citations
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Journal ArticleDOI
Presynaptic organelles and junctional integrity.
TL;DR: The identification of synaptic bulbs at the electron accompanied by attempts to study their fate after microscope level and the description of their major the interruption of parent fibers are described.
Journal ArticleDOI
Structural destabilization of synaptosomal particles by lysis and sequential chemical treatments.
TL;DR: The final result of the sequential treatments was a sediment containing a high proportion of synaptic particles, about half of which had lost their presynaptic junctional membranes.
Journal ArticleDOI
Association of Nerve Fibers and Plasma Cells in Abnormal Human Nasal Respiratory Mucosa
Nikolajs Cauna,Dzidra Cauna +1 more
TL;DR: Degeneration of sensory and autonomic nerve endings and intimate association of preterminal nerve fibers with plasma cells are described in eight patients suffering from nasal congestion, suggesting that the degeneration of nerves may be caused by autoimmune reaction as a result of tissue exposure to infection or drugs.
Journal ArticleDOI
Enlargement of synaptic vesicles in degenerating nerve endings: A comparison between cat and monkey
TL;DR: Comparison of the results obtained indicate that the changes in synaptic vesicles of optic nerve endings in the lateral geniculate nucleus of cats and monkeys are faster in cats than in monkeys.
Journal ArticleDOI
The distribution of primary afferents to the cochlear nuclei in the domestic hen (Gallus domesticus).
Jan Egil Wold,J. G. Hall +1 more
TL;DR: The normal anatomy of the three cochlear nuclei in the hen, the nucleus laminaris, the nuclei angularis and the nucleus magnocellularis is described and all three nuclei are shown to receive primary cochLear fibers (silver impregnation methods).
References
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Journal ArticleDOI
Hemorrhages into peripheral nerves in association with leukemia.
Book ChapterDOI
Synaptic Morphology in the Normal and Degenerating Nervous System
E.G. Gray,R.W. Guillery +1 more
TL;DR: It is emphasized that, in addition to transmission of impulses, the organization of neuroneuronal junctions is likely to include other important properties that cannot be ignored when the morphology of synaptic contacts is being considered.
Journal Article
Electron microscopy of experimental degeneration in the avian optic tectum.
E. G. Gray,L. H. Hamlyn +1 more
TL;DR: In this paper, the authors used the simplified classification of the tectal layers used by Cragg, Evans & Hamlyn (1954) modified from van Gehuchten (1892) to study the effects of axons and their terminals.
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Electron microscopy of experimental degeneration in the avian optic tectum.
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