Journal ArticleDOI
Estimation of the fecund life span of Wuchereria bancrofti in an endemic area
Reads0
Chats0
TLDR
A stochastic approach appropriate for general use in endemic communities was applied to estimate the average yearly instantaneous rate of loss of W. bancrofti microfilaraemia from infected individuals, and gain by uninfected individuals, from longitudinal data, and the results suggest that the life span is at the lower end of previous estimates.Abstract:
A stochastic approach appropriate for general use in endemic communities was applied to estimate the average yearly instantaneous rate of loss of Wuchereria bancrofti microfilaraemia from infected individuals, and gain by uninfected individuals, from longitudinal data. This method was shown to give similar results (i.e., the rate of loss was independent of age, while the rate of gain differed significantly between age classes) to a previously used method based on transmision interruption, provided that the intersurvey interval was >5 years. The method was used to estimate the fecund life span of W. bancrofti in an endemic area at 5 years. The results suggest that the life span is at the lower end of previous estimates.read more
Citations
More filters
Journal ArticleDOI
Nutrition, immunity and infection: From basic knowledge of dietary manipulation of immune responses to practical application of ameliorating suffering and improving survival
TL;DR: Investigation of nutrition-immunity interactions in undernourished individuals found that nutritional deficiency is commonly associated with impaired immune responses, particularly cell-mediated immunity, phagocyte function, cytokine production, secretory antibody response, antibody affinity, and the complement system.
Book
Worms and Human Disease
TL;DR: The trematodes the cestodes the acanthocephala the nematodes other groups epidemiological aspects of helminth infections immunological aspects of Helminth Infections helminthsological techniques.
Journal ArticleDOI
Modulation of Macrophage Cytokine Production by ES-62, a Secreted Product of the Filarial Nematode Acanthocheilonema viteae
Helen S. Goodridge,Emma H. Wilson,William Harnett,Carol Campbell,Margaret M. Harnett,Foo Y. Liew +5 more
TL;DR: Exposure to ES-62 renders macrophages subsequently unable to produce Th1/proinflammatory cytokines, which likely contributes to the generation of immune responses with an anti-inflammatory Th2 phenotype, a well-documented feature of filarial nematode infection.
Journal ArticleDOI
The impact of 34 years of massive DEC chemotherapy on Wuchereria bancrofti infection and transmission: the Maupiti cohort.
TL;DR: The results of two surveys in 1985 and 1989 led to the hope that the eradication of lymphatic filariasis had been achieved, but these results were partially confirmed in 1999.
Journal ArticleDOI
EPIFIL: the development of an age-structured model for describing the transmission dynamics and control of lymphatic filariasis.
Rachel Norman,M. S. Chan,A. Srividya,S P Pani,Kapa D. Ramaiah,Perumal Vanamail,Edwin Michael,Pradeep Das,Donald A. P. Bundy +8 more
TL;DR: The model is expanded to examine the effects of control options against filariasis by incorporating the impact of age structure of the human community and by addressing explicitly the dynamics of parasite transmission from and to the vector population.
References
More filters
Journal Article
Estimation of incidence and recovery rates of Plasmodium falciparum parasitaemia from longitudinal data
TL;DR: The method was applied to data on falciparum malaria from the West African savanna and the findings suggested that immunity increases the rate of recovery from patent parasitaemia by a factor of up to 10, and also reduces the number of episodes of patent parasites resulting from one inoculation.
Journal ArticleDOI
Estimation of age-specific rates of acquisition and loss of Wuchereria bancrofti infection
Perumal Vanamail,S. Subramanian,P. K. Das,S. P. Pani,Rajagopalan Pk,Donald A. P. Bundy,Bryan T. Grenfell +6 more
TL;DR: The results suggest that the age-distribution of bancroftian filariasis is primarily determined by age-dependency in the rate of acquisition of infection.
Journal Article
Analysis of the Wuchereria bancrofti population in the people of American Samoa.
N. G. Hairston,L. A. Jachowski +1 more
TL;DR: Estimates of reproduction and survival at all stages in their life-histories for Wuchereria bancrofti are obtained, and the construction of a complete ecological life-table for the parasite is a distinct possibility.
Journal ArticleDOI
Bancroftian filariasis in Pondicherry, south India: 1. Pre-control epidemiological observations.
TL;DR: A 5-year Integrated Vector Management (IVM) project was implemented in Pondicherry, South India, for the control of Bancroftian filariasis as discussed by the authors.