Journal ArticleDOI
Etiological factors for the persistence of endemic goiter in selected areas of Siddharthnagar district in Eastern Uttar Pradesh, India.
TLDR
Consumption of inadequately iodized salt and cyanogenic plant foods containing goitrogenic/anti-thyroidal substances by the people of the studied region are possible reasons for the persistence of goiter during the post salt iodination phase.Abstract:
AIM To assess the prevalence of goiter, state of iodine nutrition of the population, consumption pattern of common goitrogenic food, and distribution of iodine through edible salt in selected CD Blocks of Siddharthnagar district in Eastern Uttar Pradesh. METHODS Goiter survey among 1,862 school children, aged 6-12 years, of both sexes, and analysis of iodine (I) and thiocyanate (SCN) in 240 urine samples, and iodine content in 210 edible salt samples collected from the selected study areas. RESULTS The prevalence of goiter was 26.3% (grade 1: 23.2%; grade 2: 3.1%). Median urinary iodine level was 6.0 microg/dl, and 42% had concentration 15 ppm; 82.9% had < 15 ppm. CONCLUSION Consumption of inadequately iodized salt and cyanogenic plant foods containing goitrogenic/anti-thyroidal substances by the people of the studied region are possible reasons for the persistence of goiter during the post salt iodination phase.read more
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Journal Article
Endemic Goitre in the Sudan despite Long-Standing Programmes for the Control of Iodine Deficiency disorders/Goitre Endemique Au Soudan Malgre Les Programmes Permanents De Controle Des Troubles Dus a la Carence En iode/Persistencia del Bocio Endemico En Sudan Pese a la Aplicacion Desde Hace Tiempo De Programas Para Controlar Los Trastornos Por Deficiencia De Yodo
TL;DR: IDDs still constitute a public health problem throughout urban areas in the Sudan and iodine deficiency appears to be the main etiological factor involved.
Journal ArticleDOI
Endemic goitre in the Sudan despite long-standing programmes for the control of iodine deficiency disorders
TL;DR: In this article, the authors describe the status of iodine deficiency disorders (IDDs) in the Sudan more than 25 years after the initiation of IDD control programmes and explore the causes of endemic goitre in the country.
Journal ArticleDOI
Iodine, Thiocyanate and the Thyroid
TL;DR: In the semi-arid region of earth, the consumption of cyanogenic food (thiocyanate precursor) is relatively high and many regions are environmentally iodine deficient therefore the people are at the risk of iodine deficiency disorders (IDD).
Journal Article
Synergic actions of polyphenols and cyanogens of peanut seed coat (Arachis hypogaea) on cytological, biochemical and functional changes in thyroid.
TL;DR: Data indicate that PSC could be a novel disruptor of thyroid function, due to synergistic actions of phenolic as well as cyanogenic constituents.
References
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Journal ArticleDOI
A new method for the estimation of micro quantities of cyanide and thiocyanate
Journal ArticleDOI
Residual goitre in the postiodization phase: iodine status, thiocyanate exposure and autoimmunity
Raman K. Marwaha,Nikhil Tandon,Nandita Gupta,Asis Kumar Karak,Kusum Verma,Narayana Kochupillai +5 more
TL;DR: Assessment of goitre prevalence, thyroid functional status and cause of residualGoitre among school children in the postsalt iodization phase in India found no change in either prevalence or functional status.