Journal ArticleDOI
Experimental gingivitis around deciduous teeth in children with Down's syndrome.
TLDR
A controlled study to determine the extent and the quality of the differences in the early periodontal tissue response towards dental plaque in the deciduous dentition of DS children and matched control children confirmed earlier results from epidemiological studies.Abstract:
Epidemiological studies have shown that there is a high prevalence and rapid progression of periodontal disease in children with Down's Syndrome (DS). In this respect, DS children exhibit a markedly different response compared with healthy children. In order to understand the reasons for this difference, a controlled study was set up to determine the extent and the quality of the differences in the early periodontal tissue response towards dental plaque in the deciduous dentition of DS children and matched control children. In a preliminary investigation, the gingival health was estimated by determining the bleeding tendency. 9 healthy children were selected from a group of 14 and matched with 9 DS children with respect to plaque development, sulcus depth and age. The DS children had a higher bleeding tendency than the matched controls. In the DS children, moreover, a correlation was found between bleeding tendency and age. No such correlation was found in the controls. After a period of intensive oral hygiene, all cleaning of teeth was discontinued for 21 days. The amount of plaque according to the plaque index, the gingival health according to the gingival index, and the amount of crevicular leucocytes and gingival exudate were assessed at days 0, 7, 14 and 21. During the experimental phase of the study, the amount of plaque increased at a similar rate in both groups. In the DS children, the development of gingival inflammation started earlier and was more extensive. It increased after day 14, whereas in the control children, the gingival inflammation seemed to stabilize at this time. The results of the present experimental study thus confirm earlier results from epidemiological studies.(ABSTRACT TRUNCATED AT 250 WORDS)read more
Citations
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Journal ArticleDOI
Plaque-induced gingivitis: Case definition and diagnostic considerations.
TL;DR: The purpose of the present review is to summarize the evidence on clinical, biochemical, microbiologic, genetic markers as well as symptoms associated with plaque-induced gingivitis and to propose a set of criteria to define GC.
Journal ArticleDOI
The role of systemic conditions and disorders in periodontal disease
Robert J. Genco,Harald Löe +1 more
Journal ArticleDOI
Genetic Influences in Caries and Periodontal Diseases
TL;DR: A turning point is identified at about 1960, when the periodontal research community turned away from genetics in favor of microbiology research, and investigators have re-initiated the search for the hereditary component in susceptibility to common adultperiodontal disease.
Journal ArticleDOI
Significance of oral health in persons with Down syndrome: a literature review
TL;DR: An overview of the current literature concerning the orofacial problems confronting patients with DS is given, to explain the different treatment modalities available.
Journal ArticleDOI
Influences of systemic diseases on periodontitis in children and adolescents.
Joerg Meyle,José R. Gonzales +1 more
TL;DR: Systemic diseases affecting the host response as primary immunodeficiencies or secondary defects caused by lack of nutrients or changes in the local tissues are very often accompanied by early-onset prepubertal periodontitis.
References
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Journal ArticleDOI
Periodontal Disease in Pregnancy II. Correlation Between Oral Hygiene and Periodontal Condition
John Silness,Harald Löe +1 more
TL;DR: In this paper, the correlation between oral hygiene and periodontal condition was investigated in the context of pregnant women with Periodontal Disease in Pregnancy II (PDI II).
Journal ArticleDOI
Periodontal disease in pregnancy. i. prevalence and severity.
Harald Löe,John Silness +1 more
TL;DR: (1963).
Journal ArticleDOI
Role of the polymorphonuclear leukocyte in periodontal health and disease
TL;DR: Evidence for lysosomal enzymes being at least partly responsible for the tissue destruction seen in periodontal disease is presented, and it may prove beneficial to use gingival crevicular PMN activity as a reliable clinical index of disease activity.