Journal ArticleDOI
Factors affecting the determination of bound ascorbic acid in blood serum or animal tissues.
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It was demonstrated that the amount of bound ascorbic acid determined to be present in blood serum or plasma depended upon the time and temperature of hydrolysis, the sample size, and the presence or absence of several constituents of blood or tissues.About:
This article is published in Archives of Biochemistry and Biophysics.The article was published on 1960-07-01. It has received 10 citations till now. The article focuses on the topics: Ascorbic acid & Blood serum.read more
Citations
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Journal ArticleDOI
Extracellular ascorbic acid in lung
R.J. Willis,C.C. Kratzing +1 more
TL;DR: The results were taken to indicate the presence of an extracellular pool of ascorbic acid in lung which is maintained even during scurvy.
Journal ArticleDOI
Pharmacokinetics of ascorbic acid in man
TL;DR: The pharmacokinetic characteristics of ascorbic acid have been investigated in normal adult volunteers, using a two-compartment open model, with a profound change in the pharmacokinetics of the vitamin.
Journal ArticleDOI
The separation of bound ascorbic acid from rat adrenals by gel filtration.
Rosemary Fiddick,H. Heath +1 more
TL;DR: A new method is described for the study of bound ascorbic acid using extracts of adrenals from rats injected previously with l -[I-14C]ascorbic acid separated by gel filtration on Sephadex G-50 columns into eight fractions thought to represent protein or polypeptide-bound forms of ascorBic acid.
Journal ArticleDOI
Effect of amino acids, peptides and related compounds on the autooxidation of ascorbic acid
J.E. Fleming,K.G. Bensch +1 more
TL;DR: The finding that 3-methyl histidine had a significant inhibitory effect on ascorbic acid oxidation whereas 1-methylhistidine had no effect suggests that ascorBic acid forms complexes with certain compounds and that this interaction stabilizes ascor bic acid against auto-oxidation.
Book ChapterDOI
Ascorbic acid in man and animals.
W. Eugene Knox,M.N.D. Goswami +1 more
TL;DR: This chapter reviews the chemical, biochemical, and physiological properties of ascorbic acid and attempts to summarize the significant knowledge gained from nutritional investigations about the nature and prevention of scurvy in animals.
References
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Journal ArticleDOI
The determination of ascorbic acid in small amounts of blood serum
Journal ArticleDOI
The determination of bound ascorbic acid in liver tissue.
Journal ArticleDOI
Failure to find bound ascorbic acid in plasma
Frederick Sargent,Ralph Golden +1 more
TL;DR: In both these series, log E, calculated on the basis of no reaction, agreed remarkably well with those of the standard ascorbic acid solution, and one may conclude that the method of continuous variations did not indicate.