Factors influencing pulmonary resistance.

TL;DR: Obesity appears to be a particularly important issue for severe asthma, and there are also plausible biological mechanisms whereby obesity could be expected to either cause or worsen asthma.

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Journal ArticleDOI

Site of Airway Obstruction in Asthma as Determined by Measuring Maximal Expiratory Flow Breathing Air and a Helium-Oxygen Mixture

P. J. Despas, +2 more

- 01 Dec 1972 -

Journal of Clinical Investigation

TL;DR: The site of airway obstruction varies among asthmatics and that the site of obstruction is not detectable by measurement of the usual parameters of lung mechanics, which indicates that maximum expiratory flow-volume rates in normal subjects are dependent on gas density.

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Journal ArticleDOI

Respiratory system mechanics in sedated, paralyzed, morbidly obese patients.

Paolo Pelosi, +6 more

- 01 Mar 1997 -

Journal of Applied Physiology

TL;DR: The data suggest that obese subjects during sedation and paralysis are characterized by hypoxemia and marked alterations of the mechanical properties of the respiratory system, largely explained by a reduction in lung volume due to the excessive unopposed IAP.

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Journal ArticleDOI

Clinical applications of forced oscillation to assess peripheral airway function

M. Goldman, +2 more

- 25 Aug 2005 -

Respiratory Physiology & Neurobiology

TL;DR: Respiratory impedance is calculated by computer-assisted methods that yield separate resistive and reactive components that yield characteristic patterns of response in low frequency resistance and reactance measures that appear to be closely correlated with each other.

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