Open AccessJournal Article
Factors influencing the development of metabolic bone disease in primary biliary cirrhosis.
Núria Guañabens,Albert Parés,Mariñoso L,Brancós Ma,Carlos Piera,Serrano S,Rivera F,Joan Rodés +7 more
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TLDR
The results of this study indicate that osteodystrophy in primary biliary cirrhosis is characterized mainly by "low-turnover" osteoporosis, which is related to the duration of the liver disease, postmenopausal condition, and calcium malabsorption.About:
This article is published in The American Journal of Gastroenterology.The article was published on 1990-10-01 and is currently open access. It has received 148 citations till now. The article focuses on the topics: Bone disease & Osteomalacia.read more
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ACG Clinical Guideline: Primary Sclerosing Cholangitis.
TL;DR: Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and may require liver transplantation and ursodeoxycholic acid is used by many on an empirical basis.
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Guidelines on the management of osteoporosis associated with chronic liver disease
TL;DR: The scope of these guidelines is to review the assessment and diagnosis of osteoporosis, the therapeutic agents available, and the way in which they can be used in patients with chronic liver disease to prevent osteoporeosis with the aim of reducing fracture rate.
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AGA technical review on osteoporosis in hepatic disorders
TL;DR: The general biology and pathogenesis of osteoporosis, including its relationship with inflamma-tory states, diagnostic tools, and clinical utility of bone densitometry, has been reviewed elsewhere.
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Osteoporosis and bone mineral metabolism disorders in cirrhotic patients referred for orthotopic liver transplantation.
A. Monegal,M. Navasa,Núria Guañabens,Pilar Peris,F. Pons,M J Martínez de Osaba,A. Rimola,Joan Rodés,José Muñoz-Gómez +8 more
TL;DR: Reduced bone formation and significant disorders of bone mineral metabolism, such as vitamin D deficiency, reduced parathyroid hormone levels, and hypogonadism are involved in patients referred for orthotopic liver transplantation.
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Role of hyperbilirubinemia in the impairment of osteoblast proliferation associated with cholestatic jaundice.
TL;DR: The hypothesis that hyperbilirubinemia or possibly other photolabile substances impair osteoblast proliferative capacity and thus may play a major role in the pathogenesis of the osteoporosis associated with CCLD is supported.