Journal ArticleDOI
Fetal outcome following intrauterine amantadine exposure.
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TLDR
A 34-year-old woman who had used amantadine to prevent relapse of her multiple sclerosis throughout two of her pregnancies who subsequently delivered two normal infants is reported.About:
This article is published in Reproductive Toxicology.The article was published on 1991-01-01. It has received 15 citations till now. The article focuses on the topics: Amantadine Hydrochloride & Amantadine.read more
Citations
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Journal ArticleDOI
Pneumonia in pregnancy.
William Goodnight,David E. Soper +1 more
TL;DR: Prompt diagnosis and treatment with contemporary antimicrobial therapy and intensive care unit management of respiratory compromise has reduced the maternal morbidity and mortality due to pneumonia in pregnancy.
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Pharmacotherapy for pregnant women with addictions.
TL;DR: Antiaddiction medications are important in the treatment of pregnant women with opioid and nicotine dependence and are of growing importance in the Treatment of alcohol and stimulant dependence.
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Viral respiratory disease in pregnancy.
TL;DR: Pregnant women have an increased susceptibility to viral respiratory diseases and should be treated aggressively with supportive care and antiviral medications, as the significant risk of maternal mortality outweighs the potential fetal risks.
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Treatment of community-acquired lower respiratory tract infections during pregnancy
TL;DR: There are few data specifically related to pregnant women with different types of LRTI, and β-Lactam and macrolide antibiotics remain the antibiotics of choice in terms of both pathogen coverage and safety in pregnancy.
References
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Journal ArticleDOI
Diphosphonates and inhibition of bone mineralisation
Journal ArticleDOI
The toxicologic and pharmacologic properties of amantadine hydrochloride
TL;DR: Amantadine HCl was adequately tolerated on long term chronic administration to rats, dogs, and monkeys at doses more than 13 to 33 times the projected human doses without evidence of organ pathology and studies in rats and rabbits revealed good reproductive tolerance and no indication of teratogenicity.
Journal Article
Absorption, distribution and excretion of amantadine hydrochloride
TL;DR: The excretion pattern in man that results from multiple dosage is consistent with predictions made from single dose experiments, and the rate of excretion of the drug is first order.
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The influence of pregnancy on disability from multiple sclerosis: a population-based study in Middlesex County, Ontario.
TL;DR: There was no association between disability and total number of term pregnancies, timing of pregnancy relative to onset of MS, or either onset or worsening of MS in relation to a pregnancy.