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Journal ArticleDOI

Fluctuation driven ratchets: Molecular motors.

Astumian Rd, +1 more
- 14 Mar 1994 - 
- Vol. 72, Iss: 11, pp 1766-1769
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TLDR
Even if the net force is always zero, flow is induced by a fluctuation of the energy barrier, but only at flipping times roughly in between the adiabatic adjustment times on the left and right of the barrier.
Abstract
The motion of a heavily damped Brownian particle in a periodic potential subject to a dichotomously fluctuating perturbation is considered. We show that even if the net force is always zero, flow is induced by a fluctuation of the energy barrier, but only at flipping times roughly in between the adiabatic adjustment times on the left and right of the barrier. Predictions of our model are consistent with recent experimental data obtained by Svoboda et al. [Nature (London) 365, 721\char21{}727 (1993)] for a single kinesin molecule moving along a biopolymer.

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Microfluidics: Fluid physics at the nanoliter scale

TL;DR: A review of the physics of small volumes (nanoliters) of fluids is presented, as parametrized by a series of dimensionless numbers expressing the relative importance of various physical phenomena as mentioned in this paper.
Journal ArticleDOI

Brownian motors: noisy transport far from equilibrium

TL;DR: In this paper, the main emphasis is put on directed transport in so-called Brownian motors (ratchets), i.e. a dissipative dynamics in the presence of thermal noise and some prototypical perturbation that drives the system out of equilibrium without introducing a priori an obvious bias into one or the other direction of motion.
Journal ArticleDOI

Optical trapping and manipulation of neutral particles using lasers

TL;DR: Early developments in the field leading to the demonstration of cooling and trapping of neutral atoms in atomic physics and to the first use of optical tweezers traps in biology are reviewed.
Journal ArticleDOI

Artificial Brownian motors: Controlling transport on the nanoscale

TL;DR: In this paper, the constructive role of Brownian motion is exemplified for various physical and technological setups, which are inspired by the cellular molecular machinery: the working principles and characteristics of stylized devices are discussed to show how fluctuations, either thermal or extrinsic, can be used to control diffusive particle transport.
Journal ArticleDOI

Thermodynamics and Kinetics of a Brownian Motor

TL;DR: Fluctuation-driven transport is one mechanism by which chemical energy can directly drive the motion of particles and macromolecules and may find application in a wide variety of fields, including particle separation and the design of molecular motors and pumps.