Journal ArticleDOI
Genotoxicity and cytotoxicity of the epoxy resin-based root canal sealer AH plus.
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TLDR
No genotoxicity and mutagenicity were revealed by AH Plus, and these data should be taken into consideration when deciding about a root canal sealer.About:
This article is published in Journal of Endodontics.The article was published on 1999-02-01. It has received 80 citations till now. The article focuses on the topics: Root canal & Genotoxicity.read more
Citations
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Cytotoxicity of new resin-, calcium hydroxide- and silicone-based root canal sealers on fibroblasts derived from human gingiva and L929 cell lines.
Ayce Unverdi Eldeniz,Ayce Unverdi Eldeniz,Kamal Mustafa,Kamal Mustafa,Dag Ørstavik,Jon E. Dahl +5 more
TL;DR: Toxicity varied but RC Sealer and GuttaFlow were the least toxic new sealers.
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Biocompatibility of dental materials used in contemporary endodontic therapy: a review. Part 2. Root-canal-filling materials.
C. H. J. Hauman,Robert M. Love +1 more
TL;DR: This paper is a review of the biocompatibility of contemporary orthograde and retrograde root-canal-filling materials.
Journal ArticleDOI
Evaluation of apical sealing ability and adaptation to dentine of two resin-based sealers.
Semra Sevimay,A. Kalayci +1 more
TL;DR: AH plus sealer has better apical sealing ability and adaptation to dentine than EndoRez sealer, and both sealers had better adaptation and penetration in coronal and middle thirds than apical third of root canal.
Obturation of the radicular space
TL;DR: It is hypothesized that the penetration of radioactive iodine into a poorly filled root canal in vitro is analogous to fluid percolation into the canal of in situ pulpless teeth with incomplete canal obliteration, which might well explain the paradox of the periradicular lesion associated with a noninfected pulpless tooth.
References
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Revised methods for the salmonella mutagenicity test
Dorothy M. Maron,Bruce N. Ames +1 more
TL;DR: Two new tester strains, a frameshift strain and a strain carrying an ochre mutation on a multicopy plasmid (TA102), are added to the standard tester set and two substitutions are made in diagnostic mutagens to eliminate MNNG and 9-aminoacridine.
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Genotoxicity of dental materials
TL;DR: This investigation gives several lines of evidence that most dental materials tested yield 'positive' results in at least one of the genotoxicity tests, however, with effects ranging from 'borderline' to 'strong positive'.
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Biologic effects of dental materials
TL;DR: In this paper, a method for evaluating the biologic properties of anterior tooth filling materials before recommending them for common use is proposed, which consists of a screening test which allows objective recording of the cytotoxicity of the material and its components separately and a usage test.
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Validation of the SOS / umu test using test results of 486 chemicals and comparison with the Ames test and carcinogenicity data
Georg Reifferscheid,Jürgen Heil +1 more
TL;DR: The results presented here clearly demonstrate that a chemical which induces the expression of the umu operon can be regarded a rodent carcinogen with a high degree of certainty (93%).
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Biologic effects of dental materials. 1. Toxicity of root canal filling materials on HeLa cells in vitro.
TL;DR: Twelve different root canal filling materials were tested regarding cytotoxicity in vitro with a new method which allowed complete material-cell contact throughout the entire setting time, and chloropercha, after chloroform evaporation, had the lowest toxic effect of all set materials.