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Glucocorticoid-induced myopathy: Pathophysiology, diagnosis, and treatment.

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TLDR
The pathophysiology behind glucocorticoid-induced myopathy, along with diagnostic features and treatment, are discussed, and patients with Cushing's syndrome are referred for treatment.
Abstract
Glucocorticoid-induced myopathy is the most common type of drug-induced myopathy Nearly 60% of patients with Cushing's syndrome have muscle weakness Glucocorticoid-induced muscle atrophy affects mainly fast-twitch glycolytic muscle fibers (type IIb fibers) This brief review will discuss the pathophysiology behind glucocorticoid-induced myopathy, along with diagnostic features and treatment

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Fear and lethality in snowshoe hares: the deadly effects of non-consumptive predation risk

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Chronic hypoventilation syndromes and sleep-related hypoventilation

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References
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The adrenal cortex.

Dn. Orth
TL;DR: The report issued by Dr. Cook states bluntly that education of the public in the principles of hygiene has been neglected and the present need is to emphasize the unsatisfactory basis on which much of thepublic health work has been attempted.
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Mechanisms of glucocorticoid-induced myopathy.

TL;DR: Recent progress in the understanding of the glucocorticoid-induced muscle atrophy should allow to define new therapies aiming to minimize this myopathy, which is characterized by fast-twitch or type II muscle fiber atrophy illustrated by decreased fiber cross-sectional area and reduced myofibrillar protein content.
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Glucocorticoids and muscle catabolism.

TL;DR: In certain catabolic conditions, including sepsis, an interaction between glucocorticoids and proinflammatory cytokines is important for the stimulation of muscle protein breakdown.
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Muscle cachexia: current concepts of intracellular mechanisms and molecular regulation.

TL;DR: An understanding of the mechanisms regulating muscle protein breakdown is important for the development of therapeutic strategies aimed at treating or preventing muscle cachexia in patients with severe injury, sepsis, cancer, and perhaps other catabolic conditions as well.
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Steroid myopathy in connective tissue disease

TL;DR: In eight women with polymyositis, weakness developed during high dose prednisone therapy, and urinary creatine excretion proved to be the most sensitive laboratory indicator for clinical diagnosis and for monitoring patient improvement.
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