Journal ArticleDOI
Gray matter abnormalities associated with duration of untreated psychosis.
Julia Lappin,Kevin Morgan,Craig Morgan,Gerard Hutchison,Xavier Chitnis,John Suckling,Paul Fearon,Philip McGuire,Peter B. Jones,Julian Leff,Robin M. Murray,Paola Dazzan +11 more
Reads0
Chats0
TLDR
Temporal gray matter reductions are more marked in patients with a long DUP, which could reflect a progressive pathological process that is active prior to treatment and could be associated with a more insidious onset of illness and a later presentation to services.About:
This article is published in Schizophrenia Research.The article was published on 2006-04-01. It has received 94 citations till now. The article focuses on the topics: dup & Psychosis.read more
Citations
More filters
Journal ArticleDOI
Co-Planar Stereotaxic Atlas of the Human Brain—3-Dimensional Proportional System: An Approach to Cerebral Imaging, J. Talairach, P. Tournoux. Georg Thieme Verlag, New York (1988), 122 pp., 130 figs. DM 268
Journal ArticleDOI
What Happens After the First Episode? A Review of Progressive Brain Changes in Chronically Ill Patients With Schizophrenia
TL;DR: Overall, the findings suggest continuous progressive brain tissue decreases and lateral ventricle volume increases in chronically ill patients, up to at least 20 years after their first symptoms, are suggested.
Journal ArticleDOI
The Myth of Schizophrenia as a Progressive Brain Disease
TL;DR: Mental health professionals need to join with patients and their families in understanding that schizophrenia is not a malignant disease that inevitably deteriorates over time but rather one from which most people can achieve a substantial degree of recovery.
Journal ArticleDOI
Brain Derived Neurotropic Factor in First –Episode Psychosis
Peter F. Buckley,Anilkumar Pillai,Anilkumar Pillai,Denise R. Evans,Denise R. Evans,Edna Stirewalt,Sahebarao P. Mahadik,Sahebarao P. Mahadik +7 more
TL;DR: Low BDNF levels at the onset of psychosis suggest that it may contribute to the pathogenesis of schizophrenia and/or perhaps could be a helpful neurobiological marker for possible early treatment intervention.
Journal ArticleDOI
Early signs, diagnosis and therapeutics of the prodromal phase of schizophrenia and related psychotic disorders
TL;DR: Preliminary data suggest that low doses of atypical antipsychotic medications augmented by psychosocial treatments may delay the onset of psychosis in some individuals.
References
More filters
Journal ArticleDOI
Co-Planar Stereotaxic Atlas of the Human Brain—3-Dimensional Proportional System: An Approach to Cerebral Imaging, J. Talairach, P. Tournoux. Georg Thieme Verlag, New York (1988), 122 pp., 130 figs. DM 268
Journal ArticleDOI
Voxel-Based Morphometry—The Methods
John Ashburner,Karl J. Friston +1 more
TL;DR: In this paper, the authors describe the steps involved in VBM, with particular emphasis on segmenting gray matter from MR images with non-uniformity artifact and provide evaluations of the assumptions that underpin the method, including the accuracy of the segmentation and the assumptions made about the statistical distribution of the data.