Hypermetabolic Calcified Lymph Nodes on 18Fludeoxyglucose-Positron Emission Tomography/Computed Tomography in a Case of Treated Ovarian Cancer Recurrence: Residual Disease or Benign Formation?
Alexandra Nikaki,Athanasios Alexopoulos,Fani Vlachou,Vasiliki Filippi,Ioannis Andreou,Vasiliki Rapti,Konstantinos Gogos,K. Dalianis,Roxani Efthymiadou,V. Prassopoulos +9 more
Reads0
Chats0
TLDR
Both CT corrected and uncorrected PET images showed hypermetabolism in the massively calcified lymph nodes in the neck, mediastinum, axilla and abdomen, indicative of active residual disease.Abstract:
The contribution of positron emission tomography/computed tomography (PET/CT) with 18F-fludeoxyglucose (FDG) in evaluating ovarian cancer recurrence even after a prolonged disease-free interval, and in therapy response is well-described. Calcifications observed in CT, although usually attributed to benign conditions, may actually represent active disease. Such an example of calcified formations is psammoma bodies. We present a case of 56-y. o. patient with ovarian cancer relapse at the supraclavicular area 18 years after complete response and disease-free interval. The patient received chemotherapy and underwent 18F-FDG-PET/CT for the evaluation of treatment response. Both CT corrected and uncorrected PET images showed hypermetabolism in the massively calcified lymph nodes in the neck, mediastinum, axilla and abdomen, indicative of active residual disease.read more
Citations
More filters
Journal ArticleDOI
The role of FDG PET/CT in the evaluation of treatment response in a case of calcified ovarian metastases.
TL;DR: In this article, a case of serous papillary ovarian cancer with extensive abdomino-pelvic calcified metastases referred for evaluation of therapy response was evaluated using PET/computed tomography (PET/CT) images.
References
More filters
Journal ArticleDOI
Calcifications in mucinous and serous cystic ovarian tumors.
Susumu Okada,Yoshiharu Ohaki,Kohei Inoue,Takashi Kawamura,Toshihiko Hayashi,Tomoyasu Kato,Tatsuo Kumazaki +6 more
TL;DR: CT was not sufficiently sensitive in the detection of intra-cystic calcification in mucinous tumors and psammoma bodies in serous tumors, however, the presence of intramural calcifications may be a good indicator of mucinous tumor formation.
Journal ArticleDOI
Long-term oncological outcomes of ovarian serous carcinomas with psammoma bodies : A novel insight into the molecular pathogenesis of ovarian epithelial carcinoma
Takeshi Motohara,Hironori Tashiro,Yo Miyahara,Isao Sakaguchi,Hideyuki Ohtake,Hidetaka Katabuchi +5 more
TL;DR: The results suggested that the formation of psammoma bodies is associated with increased apoptotic tumor cell death related to normal TP53 function, which might contribute to the consideration of pathogenesis and to the development of prognostic prediction rules for serous carcinomas.
Journal ArticleDOI
Prevalence and significance of psammoma bodies in cervicovaginal smears in a cervical cancer screening program with emphasis on a case of primary bilateral ovarian psammocarcinoma
Teresa Pusiol,Anna Maria Parolari,Irene Piscioli,Luca Morelli,Franca Del Nonno,Stefano Licci +5 more
TL;DR: This case of primary ovarian psammocarcinoma is the first report in which the presence of malignant cells and PBs in the cervicovaginal and endometrial smears represents the first manifestation of disease.
Journal Article
Ductal adenocarcinoma of the pancreas with psammomatous calcification. Report of a case.
TL;DR: The possibility of pancreatic ductal adenocarcinoma should be considered for a localized calcified lesion in the pancreas, and osteopontin may play a significant role in the development of psammoma bodies.
Journal ArticleDOI
18F-FDG PET/CT in a patient with lymph node metastasis from ovarian adenocarcinoma.
TL;DR: This case illustrates the usefulness of PET/CT using 18F-FDG for the detection of residual viable tumoral tissue in calcified cervical lymph nodes in a woman treated 16 years earlier for a papillary serous ovarian adenocarcinoma and presenting no clinical evidence of infradiaphragmatic tumor recurrence.