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Journal ArticleDOI

Hypnotic Effect of Jujubosides From Semen Ziziphi Spinosae

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TLDR
The results suggested that the hypnotic effect of jujubosides on normal rats may be influenced by circadian rhythm and the serotonergic system may involve in the hypnotIC effect ofJujuboides.
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This article is published in Journal of Ethnopharmacology.The article was published on 2010-07-06. It has received 126 citations till now. The article focuses on the topics: Non-rapid eye movement sleep & Slow-wave sleep.

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Herbal medicine for depression, anxiety and insomnia: A review of psychopharmacology and clinical evidence

TL;DR: A review of the literature was conducted to ascertain mechanisms of action of these botanicals, in addition to a systematic review of controlled clinical trials for treatment of mood, anxiety and sleep disorders, which are common comorbid psychiatric disorders.
Journal ArticleDOI

Herbal Medicine for Anxiety, Depression and Insomnia.

TL;DR: A systematic review on herbal pharmacology in depression, anxiety and insomnia is performed to further identify modes of action of different herbal medicine, and thus provides useful information for the application of herbal medicine.
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Chemical and biological assessment of Ziziphus jujuba fruits from China: different geographical sources and developmental stages.

TL;DR: The date extracts protected PC12 cells against tBHP-induced cytotoxicity, and which also stimulated the transcriptional activity of antioxidant response element, and the antioxidative effects were varied among different dates.
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A Review of Dietary Ziziphus jujuba Fruit (Jujube): Developing Health Food Supplements for Brain Protection

TL;DR: Flavonoid, cAMP, and jujuboside could be the potential bioactive ingredients to account for the biological activities of jujubes, implying that jujube is a potential candidate for development of health supplements for prevention and/or treatment of neurological diseases.
References
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Journal ArticleDOI

Rodent models of insomnia: a review of experimental procedures that induce sleep disturbances.

TL;DR: This review critically evaluates current and putative rodent models of insomnia which could be used to screen novel hypnotics and discusses their respective advantages and pitfalls with respect to validity, feasibility and translational value to human research.
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Cyclopeptide alkaloid fraction from Zizyphi Spinosi Semen enhances pentobarbital-induced sleeping behaviors

TL;DR: It is suggested that the enhancement of Cl(-) influx by CAFZ may play an important role in the potentiation of pentobarbital-induced sleeping behaviors.
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Rapid eye movement (REM) sleep homeostatic regulatory processes in the rat: changes in the sleep-wake stages and electroencephalographic power spectra.

TL;DR: In this paper, the authors investigated physiological processes that are involved in the homeostatic regulation of REM sleep and found that selective REM sleep deprivation increased delta power but decreased theta power during residual REM sleep.
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