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Journal ArticleDOI

Immunolocalization of steroidogenic enzymes, P450scc, 3β-HSD, P450c17, and P450arom in the Hokkaido brown bear (Ursus arctos yesoensis) testis

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TLDR
Immunolocalization of steroidogenic enzymes suggests that steroidogenesis may occur not only in Leydig cells, but also in spermatids of the Hokkaido brown bear testis prior to the mating season.
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This article is published in General and Comparative Endocrinology.The article was published on 1993-12-01. It has received 65 citations till now. The article focuses on the topics: Cholesterol side-chain cleavage enzyme & Pregnenolone.

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Journal ArticleDOI

Estradiol acts as a germ cell survival factor in the human testis in vitro.

TL;DR: The novel findings of the present study together with the previously reported indirect effects of estrogens on male germ cells indicate the importance of estrogen for the normal function of the testis.
Journal ArticleDOI

Sources of oestrogen in the testis and reproductive tract of the male.

TL;DR: A lot of work is now focused on this specific area in order to clarify the role of oestrogens in the reproductive tract of the male as well as to elucidate the regulation of aromatase gene expression.
Journal ArticleDOI

Oestrogen in fluid transport in efferent ducts of the male reproductive tract

TL;DR: Although the separate roles for oestrogens and androgens in the regulation of fluid reabsorption are controversial and remain to be resolved, it is now established that loss of oestrogen receptor function in males interferes with the resorptive function of efferent ductules, a function that is essential for fertility.
Journal ArticleDOI

Oestrogen, its receptors and function in the male reproductive tract — a review

TL;DR: A new major source of oestrogen is thought to be derived from the conversion of testosterone to estradiol by P450 aromatase in germ cells of the testis and spermatozoa traversing the reproductive tract.
Journal ArticleDOI

Aromatase and estrogen receptors in male reproduction.

TL;DR: It is reported that alterations of spermatogenesis occur both in terms of the number and motility of spermatozoa and in men genetically deficient in aromatase, suggesting that endogenous estrogens are important in male reproduction.
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