Open AccessJournal Article
Impulsin in the prevention of acute respiratory diseases in school children
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This article is published in Ceskoslovenská pediatrie.The article was published on 1977-06-01 and is currently open access. It has received 9 citations till now.read more
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Palmitoylethanolamide: A Natural Body-Own Anti-Inflammatory Agent, Effective and Safe against Influenza and Common Cold
TL;DR: 6 clinical trials in a total of nearly 4000 people were performed and published last century, specifically studying PEA as a therapy for influenza and the common cold, and the results support the effectiveness and safety of PEA in flu and respiratory infections.
Journal ArticleDOI
Effect of palmitoylethanolamide–polydatin combination on chronic pelvic pain associated with endometriosis: Preliminary observations
Ugo Indraccolo,Fabrizio Barbieri +1 more
TL;DR: The palmitoylethanolamide-polydatin combination seems to be very useful in controlling chronic pelvic pain associated with endometriosis, and a multi-centre pilot study is initiated to verify the effectiveness of this treatment in controlling the chronic pelvicPain associated with EndometRIosis.
Journal Article
Palmitoylethanolamide versus a nonsteroidal anti-inflammatory drug in the treatment of temporomandibular joint inflammatory pain.
Ida Marini,Maria Lavinia Bartolucci,Francesco Bortolotti,Maria Rosaria Gatto,Giulio Alessandri Bonetti +4 more
TL;DR: These data suggest that PEA is effective in treating TMJ inflammatory pain and modulates mast cell behavior controlling both acute and chronic inflammation.
Journal ArticleDOI
New Targets in Pain, Non-Neuronal Cells, and the Role of Palmitoyletha- nolamide
TL;DR: In this paper, a review of salient pre-clinical and clinical evidence supporting non-neuronal cells as viable targets in the treatment of neuropathic pain is presented, followed by a discussion of recent proof-of-concept clinical trials demonstrating the efficacy and safety of palmi-toylethanolamide in various pain states.
Journal ArticleDOI
Evolution in pharmacologic thinking around the natural analgesic palmitoylethanolamide: from nonspecific resistance to PPAR-α agonist and effective nutraceutical
TL;DR: This review discusses scientific insights related to palmitoylethanolamide (PEA) and its progression over a period of six decades, especially in light of the work of the science sociologists, Ludwig Fleck and Thomas Kuhn, on the emergence of concepts related to the pharmacologic profile of PEA.