Journal ArticleDOI
In vitro velocity measurements in the vicinity of aortic prostheses
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TLDR
In the near vicinity of the aortic prostheses, maximum values of bulk-turbulent-shear stresses estimated from turbulence-intensity measurements and simple flow models were in the range of 10 2 –10 3 dyn/cm 2, which could damage red-blood cells and platelets and lead to thrombus formation with pulsatile flow.About:
This article is published in Journal of Biomechanics.The article was published on 1979-01-01. It has received 97 citations till now. The article focuses on the topics: Pulsatile flow.read more
Citations
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Journal ArticleDOI
The Fluid Dynamics of Heart Valves: Experimental, Theoretical, and Computational Methods
TL;DR: The function of the valves on the left side of the heart is reviewed, which shows schematically the pressures, flows, and valve positions of the mitral (inflow) and aortic valves of the left ventricle.
Journal ArticleDOI
Pulsatile flow through constricted tubes: an experimental investigation using photochromic tracer methods
TL;DR: Detailed descriptions of the transition to turbulence and of the spatial and temporal variation of the wall shear stress, particularly near the reattachment point, have not been previously reported for pulsatile flow through constricted tubes.
Journal ArticleDOI
The Björk-Shiley aortic prosthesis: flow characteristics, thrombus formation and tissue overgrowth.
TL;DR: Thrombus formation and tissue overgrowth were observed in nine Bjork-Shiley aortic prostheses recovered six months or longer after implantation, attributed to the flow characteristics of the prosthesis and the low shear in the minor outflow region.
Journal ArticleDOI
Analysis of 3D transient blood flow passing through an artificial aortic valve by Lattice–Boltzmann methods
TL;DR: The simulation of three-dimensional transient physiological flows in fixed geometries similar to a CarboMedics bileaflet heart valve at different opening angles using the Lattice Boltzmann method yields reasonable results for velocity and shear stress fields.
Journal ArticleDOI
Bileaflet, tilting disc and porcine aortic valve substitutes: in vitro hydrodynamic characteristics.
Ajit P. Yoganathan,Aurelio Chaux,Richard Gray,Yi-Ren Woo,Michele DeRobertis,Frank P. Williams,Jack M. Matloff +6 more
TL;DR: Overall in vitro fluid dynamic performance of the St. Jude valve is superior to that of the two other commonly used prostheses, especially in the small sizes.
References
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Boundary layer theory
TL;DR: The flow laws of the actual flows at high Reynolds numbers differ considerably from those of the laminar flows treated in the preceding part, denoted as turbulence as discussed by the authors, and the actual flow is very different from that of the Poiseuille flow.
Journal ArticleDOI
Acute Vascular Endothelial Changes Associated with Increased Blood Velocity Gradients
TL;DR: The purpose of this study is to quantify the acute changes in endothelial histology that are associated with an induced increase in blood velocity and to establish the “normal” endothelial cell population density as a function of stress exposure.
Journal ArticleDOI
Certain Histological and Chemical Responses of the Vascular Interface to Acutely Induced Mechanical Stress in the Aorta of the Dog
TL;DR: The flux of Evans blue dye into the intimal region increased with pressure or wall strain, with shearing stress, and with increased turbulence, and was found to be most heavy in areas of total cellular erosion.
Journal ArticleDOI
Turbulent blood flow in the ascending aorta of humans with normal and diseased aortic valves.
Paul D. Stein,Hani N. Sabbah +1 more
TL;DR: The results of this study indicate that turbulent flow can occur in the as cending aorta of subjects with normal cardiac function; and it occurs consistently in the ascending aorti of individuals with abnormal aor tic valves.
Related Papers (5)
The Björk-Shiley aortic prosthesis: flow characteristics, thrombus formation and tissue overgrowth.
Deformation and fragmentation of human red blood cells in turbulent shear flow
S.P. Sutera,M.H. Mehrjardi +1 more