Induction of anaesthesia with etomidate: haemodynamic study of 36 patients
TLDR
Although etomidate has a negative inotropic effect, the variables which were depressed remained at all times within acceptable limits.Abstract:
SUMMARY The haemodynamic effects of anaesthetic induction with i.v. etomidate have been assessed in 36 patients. The variables studied were recorded under basal conditions and 3 and 10 min after induction, before surgical stimulus. There was a reduction in cardiac output, stroke volume and arterial pressure, and a compensating increase in heart rate. Pulmonary arterial pressure and vascular resistance, central venous pressure and pulmonary capillary wedge pressure were virtually unchanged. Although etomidate has a negative inotropic effect, the variables which were depressed remained at all times within acceptable limits.read more
Citations
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Journal ArticleDOI
Inhibition of Adrenal Steroidogenesis by the Anesthetic Etomidate
TL;DR: Physicians should be aware that etomidate inhibits adrenal steroidogenesis, and they should consider treating selected patients with corticosteroids if etamidate is used.
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Clinical and molecular pharmacology of etomidate.
TL;DR: A review of etomidate's clinical and molecular pharmacologic features is presented in this paper, where the major molecular targets mediating anesthetic effects are specific γ-aminobutyric acid type A receptor subtypes.
Journal ArticleDOI
The haemodynamic effects of intravenous induction. Comparison of the effects of thiopentone and propofol.
TL;DR: It is concluded that induction of anaesthesia with propofol results in acceptable haemodynamic changes, but that the agent is more depressant to the cardiovascular system than thiopentone.
Journal ArticleDOI
A review of etomidate for rapid sequence intubation in the emergency department
Joseph M. Bergen,Daniel C. Smith +1 more
TL;DR: A review of the data available from the anesthesia literature suggests that etomidate possesses many properties that may make it the agent of choice for rapid sequence intubation in the emergency department (ED).
Journal ArticleDOI
The safety of etomidate for emergency rapid sequence intubation of pediatric patients.
TL;DR: In this article, a retrospective review of 100 consecutive patients younger than age 10 years given etomidate for RSI in the ED at two academic medical centers was performed to determine whether they developed clinically important hypotension or adrenal insufficiency.
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Thromboangiitis obliterans: methods of diagnosis of chronic occlusive arterial lesions distal to the wrist with illustrative cases
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STUDIES ON THE CIRCULATION: I. Injection Method: Physical and Mathematical Considerations
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The Hemodynamic and Respiratory Effects of Diazepam (Valium
TL;DR: Diazepam, 5–10 rag, was given intravenously to treat anxiety occurring during cardiac catheterization in 15 patients and anxiety was effectively relieved in 11 patients.
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