Interactions of metal ions with nucleotides and nucleic acids and their constituents

TLDR: The role of metal ions in ribozymes ternary metal-nucleic acid base-protein complexes metal responsive gene regulation and the zinc metalloregulatory model is studied.

Abstract: Phosphate-metal ion interactions of nucleotides and polynucleotides sugar-metal ion interactions dichotomy of metal ion binding to N1 and N7 of purines general conclusions from sold state studies of nucleotide-metal ion complexes solution studies of nucleotide-metal ion complexes - isomeric equilibria stacking interactions involving nucleotides and metal ion complexes the effect of metal ions on hydrolytic reactions of nucleotides and their phosphoesters metal complexes of sulfur-containing purine derivatives mechanistic insight from kinetic studies on the interaction of model palladium (II) complexes with nucleic acid components platinum (II)-nucleobase interactions - a kinetic approach NMR studies of oligonucleotide-metal ion interactions metal ion interactions with DNA - considerations on structure, stability and effects from metal ion binding electron transfer reactions through the double helix the role of metal ions in ribozymes ternary metal-nucleic acid base-protein complexes metal responsive gene regulation and the zinc metalloregulatory model the role of iron-sulfur proteins in gene regulation current status of structure-activity relationship of platinum anticancer drugs - activation of the trans-geometry cisplatin and derived anticancer drugs - mechanism and current status of DNA binding proteins that bind to and mediate the biological activity of platinum anticancer drug-DNA adducts interactions of metallopharmaceuticals with DNA.