J
Juewen Liu
Researcher at University of Waterloo
Publications - 450
Citations - 34818
Juewen Liu is an academic researcher from University of Waterloo. The author has contributed to research in topics: Aptamer & Deoxyribozyme. The author has an hindex of 82, co-authored 448 publications receiving 28425 citations. Previous affiliations of Juewen Liu include Urbana University & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
A Colorimetric Lead Biosensor Using DNAzyme-Directed Assembly of Gold Nanoparticles
Juewen Liu,Yi Lu +1 more
TL;DR: The concept developed here can be applied to the design of nucleic acid enzyme/nanoparticle sensors for analytes that are subject to in vitro selection, and thus can significantly expand the scope of nanomaterial applications and provide a novel approach to designing simple colorimetric biosensors.
Journal ArticleDOI
Preparation of aptamer-linked gold nanoparticle purple aggregates for colorimetric sensing of analytes
Juewen Liu,Yi Lu +1 more
TL;DR: A protocol for the preparation of aptamer-linked gold nanoparticle purple aggregates that undergo fast disassembly into red dispersed nanoparticles upon binding of target analytes is described, which has proved to be generally applicable for colorimetric sensing of a broad range of analytes.
Journal ArticleDOI
Fast Colorimetric Sensing of Adenosine and Cocaine Based on a General Sensor Design Involving Aptamers and Nanoparticles
Juewen Liu,Yi Lu +1 more
TL;DR: Aptamers are nucleic acid based binding molecules that are obtained through a combinatorial selection process known as systematic evolution of ligands by exponential enrichment (SELEX) and are emerging as a new class of molecules that can rival antibodies in terms of the broad range of molecules they can selectively bind.
Journal ArticleDOI
The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers
Carlee E. Ashley,Carlee E. Ashley,Eric C. Carnes,Genevieve K Phillips,David Patrick Padilla,Paul N. Durfee,Page A. Brown,Tracey N. Hanna,Juewen Liu,Juewen Liu,Brandy Phillips,Mark B. Carter,Nick J. Carroll,Xingmao Jiang,Darren R. Dunphy,Cheryl L. Willman,Dimiter N. Petsev,Deborah G. Evans,Atul N. Parikh,Bryce Chackerian,Walker Wharton,David S. Peabody,C. Jeffrey Brinker +22 more
TL;DR: P porous nanoparticle-supported lipid bilayers (protocells) that synergistically combine properties of liposomes and nanoporous particles are reported that allow a single protocell loaded with a drug cocktail to kill a drug-resistant HCC cell, representing a 106-fold improvement over comparable liposome.