Intracellular distribution of enzymes; the oxidation of octanoic acid by rat liver fractions.
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This article is published in Journal of Biological Chemistry.The article was published on 1948-10-01 and is currently open access. It has received 1070 citations till now. The article focuses on the topics: Intracellular.read more
Citations
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Journal ArticleDOI
Nuclei from Rat Liver: Isolation Method That Combines Purity with High Yield
Günter Blobel,Van R. Potter +1 more
TL;DR: A procedure is described that gives almost quantitative separation of clean nuclei from a homogenate of rat liver and permits further quantitative fractionation of cytoplasmic components.
Journal ArticleDOI
The effect of age on the non-haemin iron in the human brain.
B Hallgren,P Sourander +1 more
TL;DR: The most extensive and systematic investigations of histologically demonstrable iron in the brain were conducted by SPATZ (1922), which found a fine granular deposit of iron in individual oligodendroglia cells and nerve cells, mainly in the globus pallidus and in the red zone of substantia nigra.
Journal ArticleDOI
INTRACELLULAR DISTRIBUTION OF ENZYMES V. FURTHER STUDIES ON THE DISTRIBUTION OF CYTOCHROME c IN RAT LIVER HOMOGENATES
Journal ArticleDOI
Microsomal Heme Oxygenase CHARACTERIZATION OF THE ENZYME
TL;DR: The kinetics and tissue distribution of the microsomal heme oxygenase suggest that it is of major importance in the physiological degradation of hemoglobin and other hemoproteins to bile pigment.
Book ChapterDOI
[15] Isolation of liver or kidney mitochondria
Diane Johnson,Henry A. Lardy +1 more
TL;DR: This chapter describes the isolation of liver or kidney mitochondria and the method for testing the quality of mitochondria, with the exception that the mitochondrial pellet need be washed only once.
References
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Phosphorus compounds in animal tissues; extraction and estimation of desoxypentose nucleic acid and of pentose nucleic acid.
Journal ArticleDOI
Cytochemical studies of mammalian tissues; isolation of intact mitochondria from rat liver; some biochemical properties of mitochondria and submicroscopic particulate material.
Journal ArticleDOI
A modified method for the study of tissue oxidations.
Van R. Potter,C. A. Elvehjem +1 more
TL;DR: A new method for the study of tissue oxidations is described, which involves the rapid preparation of homogenized tissue suspensions by means of a simple apparatus, and the measurement of the oxygen uptake of the suspension in various dilutions.
Journal ArticleDOI
Reversible inhibition of the coupling between phosphorylation and oxidation
W. F. Loomis,Fritz Lipmann +1 more
Manometric techniques and related methods for the study of tissue metabolism.
TL;DR: This book has been designed to give the graduate JL student a working description of the methods used as a routine in the study of tissue metabolism and only methods which are likely to need the minimum equipment found normally in a biological laboratory such as a respirometer, colorimeter and centrifuge are described.