Is partial-ALPPS safer than ALPPS? A single-center experience.
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This article is published in Annals of Surgery.The article was published on 2015-04-01 and is currently open access. It has received 146 citations till now.read more
Citations
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Journal ArticleDOI
Prediction of mortality after ALPPS stage-1: an analysis of 320 patients from the international alpps registry
Erik Schadde,Dimitri A. Raptis,Andreas A. Schnitzbauer,Victoria Ardiles,Christoph Tschuor,Christoph Tschuor,Mickael Lesurtel,Eddie K. Abdalla,Roberto Hernandez-Alejandro,Elio Jovine,Marcel Cerqueira César Machado,Massimo Malagó,Ricardo Robles-Campos,Henrik Petrowsky,Eduardo de Santibañes,Pierre-Alain Clavien,Pierre-Alain Clavien +16 more
TL;DR: This analysis of the largest cohort of ALPPS patients so far identifies those patients in whom stage-2 ALPPS surgery should be delayed or even denied, and may help to make ALPPS safer.
Journal ArticleDOI
Risk Adjustment in ALPPS Is Associated With a Dramatic Decrease in Early Mortality and Morbidity.
Michael Linecker,Bergthor Björnsson,Gregor A. Stavrou,Karl J. Oldhafer,Georg Lurje,Ulf P. Neumann,René Adam,François-René Pruvot,Stefan A. Topp,Jun Li,Ivan Capobianco,Silvio Nadalin,Marcel Autran C. Machado,Sergey Voskanyan,Deniz Balci,Roberto Hernandez-Alejandro,Roberto Hernandez-Alejandro,Fernando A. Alvarez,Eduardo de Santibañes,Ricardo Robles-Campos,Massimo Malagó,Michelle L. de Oliveira,Mickael Lesurtel,Pierre-Alain Clavien,Henrik Petrowsky +24 more
TL;DR: Risk adjustment of patient selection and technique in ALPPS resulted in a continuous drop of early mortality and major postoperative morbidity, which has meanwhile reached standard outcome measures accepted for major liver surgery.
Journal ArticleDOI
Modern therapeutic approaches for the treatment of malignant liver tumours
Henrik Petrowsky,Ralph Fritsch,Matthias Guckenberger,Michelle L. de Oliveira,Philipp Dutkowski,Pierre-Alain Clavien +5 more
TL;DR: The available therapies for the treatment of malignant liver tumours are summarized, with an emphasis on surgical and ablative approaches and how they align with other therapies such as modern anticancer drugs or radiotherapy.
Journal ArticleDOI
Should ALPPS be Used for Liver Resection in Intermediate-Stage HCC?
Jan G. D’Haese,Jens Neumann,Maximilian Weniger,Sebastian Pratschke,Bergthor Björnsson,Victoria Ardiles,William C. Chapman,Roberto Hernandez-Alejandro,Oliver Soubrane,Ricardo Robles-Campos,M. Stojanovic,R. Dalla Valle,Albert C. Y. Chan,Michaela Coenen,Markus Guba,Jens Werner,Erik Schadde,Martin K. Angele +17 more
TL;DR: The ALPPS approach induces a considerable hypertrophic response in HCC patients and allows resection of intermediate-stage HCC, albeit at the cost of a 31 % perioperative mortality rate.
Journal ArticleDOI
10th Anniversary of ALPPS-Lessons Learned and quo Vadis.
Hauke Lang,Eduardo de Santibañes,Hans J. Schlitt,Massimo Malagó,Thomas M. van Gulik,Marcel Autran C. Machado,Elio Jovine,Stefan Heinrich,Giuseppe Maria Ettorre,Albert C. Y. Chan,Roberto Hernandez-Alejandro,Ricardo Robles Campos,Per Sandström,Michael Linecker,Pierre-Alain Clavien +14 more
TL;DR: Although ALPPS is now an established 2-stage hepatectomy additional data are warranted to further refine indication and technical aspects, and long-term oncological outcome results are needed to establish the place of ALPPS in patients with initially nonresectable liver tumors.
References
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Journal ArticleDOI
Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey.
TL;DR: The new complication classification appears reliable and may represent a compelling tool for quality assessment in surgery in all parts of the world.
Journal ArticleDOI
The comprehensive complication index: a novel continuous scale to measure surgical morbidity.
TL;DR: The CCI summarizes all postoperative complications and is more sensitive than existing morbidity endpoints and may serve as a standardized and widely applicable primary endpoint in surgical trials and other interventional fields of medicine.
Journal ArticleDOI
Right portal vein ligation combined with in situ splitting induces rapid left lateral liver lobe hypertrophy enabling 2-staged extended right hepatic resection in small-for-size settings.
Andreas A. Schnitzbauer,Sven A. Lang,H. Goessmann,Silvio Nadalin,Janine Baumgart,Stefan Farkas,Stefan Fichtner-Feigl,Thomas Lorf,Armin Goralcyk,Rüdiger Hörbelt,Alexander Kroemer,Martin Loss,Petra Rümmele,Marcus N. Scherer,Winfried Padberg,Alfred Königsrainer,Hauke Lang,Aiman Obed,Hans J. Schlitt +18 more
TL;DR: Two-step hepatic resection performing surgical exploration, PVL, and ISS results in a marked and rapid hypertrophy of functional liver tissue and enables curative resection of marginally resectable liver tumors or metastases in patients that might otherwise be regarded as palliative.
Journal ArticleDOI
Right portal vein ligation combined with in situ splitting induces rapid left lateral liver lobe hypertrophy enabling 2-staged extended right hepatic resection in small-for-size settings.
TL;DR: This procedure may be able to overcome the shortcomings of “conventional” two-stage hepatectomy and result in an increased number of patients who could benefit from surgical treatment despite initially unresectable hepatic malignancies due to too small future liver remnant volume.
Journal ArticleDOI
Early survival and safety of ALPPS first report of the international ALPPS registry
Erik Schadde,Victoria Ardiles,Ricardo Robles-Campos,Massimo Malagó,Marcel Cerqueira César Machado,Roberto Hernandez-Alejandro,Olivier Soubrane,Andreas A. Schnitzbauer,Dimitri A. Raptis,Christoph Tschuor,Henrik Petrowsky,Eduardo de Santibañes,Pierre-Alain Clavien +12 more
TL;DR: This is the first analysis of the ALPPS registry showing that ALPPS has increased perioperative morbidity and mortality in older patients but better outcomes in patients with CRLM.
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Prediction of mortality after ALPPS stage-1: an analysis of 320 patients from the international alpps registry
Erik Schadde,Dimitri A. Raptis,Andreas A. Schnitzbauer,Victoria Ardiles,Christoph Tschuor,Christoph Tschuor,Mickael Lesurtel,Eddie K. Abdalla,Roberto Hernandez-Alejandro,Elio Jovine,Marcel Cerqueira César Machado,Massimo Malagó,Ricardo Robles-Campos,Henrik Petrowsky,Eduardo de Santibañes,Pierre-Alain Clavien,Pierre-Alain Clavien +16 more