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Patent

Kasugamycin substituted antibacterial agents

TLDR
In this paper, the PSEUDOMONAS GENUS has been found to be ESPECIALLY ACTIVE AGAINST GRAM-NEGATIVE and GRAMPOSITIVE BACTERIA.
Abstract
5-(2AMINO - 2,3,4,6 - TETRADEOXY - 4 - SUBSTITUTED-CARBOX AMIDINO - A - D - ARABINOHEXOPYRANSOYL)-(IR:2S:3S: 4R:5R:6R) - INOSITOLS ARE SEMI-SYNTHETIC KASUGAMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL PROPERTIES. THE COMPOUND 5-(2 - AMINO - 2,3,4,6 - TETRADEOXY-4-(4-PIPERIDYLCARBOXYAMIDINO) - A - D-ARABINOHEXOPURANOSYL)-(IR:2S:3S: 4R:5R:6R)-INOSITOL HAS BEEN FOUND TO BE ESPECIALLY ACTIVE AGAINST GRAM-NEGATIVE AND GRAM-POSITIVE BACTERIA, MOST PARTICULARLY THOSE OF THE PSEUDOMONAS GENUS.

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Patent

Antibiotic complex Bu 2183

TL;DR: A novel aminoglycoside antibiotic complex named Bu-2183 is produced by fermentation of Pseudomonas sp. strain D946-B83, A.T.C. 31086 as discussed by the authors.
Patent

Kasugamycin derivatives, pharmaceutical compositions and method of use

TL;DR: In this paper, the authors proposed a method of preparing aminoglycoside derivatives and their salts, which have anti-viral activity, immuno-stimulating activity and pharmaceutical compositions comprising the same.
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Guanidio derivatives of kasugamycin and their production

TL;DR: In this article, the guanidino derivatives of kasugamycin were found to show an improved antibacterial activity against Gram negative bacteria and a decreased toxicity to man and animals.
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